“…The HCV prevalence in rural Egypt is 10 to 20-fold higher than in the United States, ranging from 2.01 to 25.47 HCV cases per 1000 person-years. The highest HCV prevalence among Egyptians was attributed to previous schistosomiasis treatment with unsafe injections (Kamal, 2017;Noreen et al, 2022) Considering this higher HCV infection prevalence in Egypt, studies declared that it represents a complicated network of social, economic, psychological, and political factors. The possible causes of hepatitis include autoimmune hepatitis or secondary to dental, obstetric, injection administration, blood transfusion, and alcohol consumption (Ayoub & Abu-Raddad, 2017; Kouyoumjian, Chemaitelly, & Abu-Raddad, 2018) Acute HCV infection is usually asymptomatic or accompanied by mild flu-like symptoms, weight loss, fatigue, muscle or joint pain, irritability, nausea, malaise, anorexia, and jaundice which rarely occurs after 2 to 26 weeks post-infection.…”