Prevalence and antimicrobial resistance profiles of Salmonella isolates in apparently healthy slaughtered food animals at Maiduguri central abattoir, Nigeria

Jajere, Saleh Mohammed; Adamu, Nuhu Bala; Atsanda, Naphtali Nayamanda; Onyilokwu, Samson Amali; Gashua, M. M.; Hambali, Idris Umar; Mustapha, Fati Bukar

doi:10.1016/s2222-1808(15)60971-9

Cited by 8 publications

(6 citation statements)

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“…Previous treatment with different types of antibacterial agents, including 3GCs and carbapenems, and visitation to hospitals, are factors that facilitate colonization of individuals by ABR salmonellae (Lugito and Cucunawangsi, 2017;Whistler et al, 2018;Adikwu et al, 2018). Animals are also important reservoirs of 3GC-and carbapenemresistant organisms (Crump and Heyderman, 2015;Whistler et al, 2018), and reports showed that these organisms are haboured by livestock in Nigeria (Jajere et al, 2015;Ejikeugwu et al, 2017;Ojo et al, 2018;. Ankpa is a heavily-populated cosmopolitan agrarian town located in Kogi State North-central, Nigeria.…”

Section: Introductionmentioning

confidence: 99%

Generic Salmonella in Asymptomatic Adult Volunteers: Occurrence, Antibiogram, Extended-Spectrum β-Lactamase Production and Carbapenem Resistance

et al. 2019

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This study was conducted to isolate generic Salmonella from stool of apparently-healthy/asymptomatic adult volunteers in Ankpa North-central Nigeria, and to determine antibacterial susceptibility, extended-spectrum β-lactamase production and carbapenem resistance. About a gram of stool was collected from 295 randomly-selected apparently-healthy/asymptomatic adult volunteers in Ankpa Kogi State, North-central Nigeria. Isolation of Salmonella was done by pre-enrichment with buffered peptone water, enrichment with Rapapport-Vassiliadis and sub-culturing on Salmonella-Shigella and MacConkey agar. Identification of the isolates to genus level was done using standard biochemical tests. Resistance of the isolates was determined by disc diffusion method. Production of ESBL was assessed by combination disc method while carbapenem resistance was determined using meropenem disc screening method. Nine (3.1%) out of 295 samples, gave positive growth of Salmonella. Of these 9 isolates, all were carbapenem (meropenem)-resistant and 1 (11.1%) was ESBL-producer. Among the isolates, all were resistant to ciprofloxacin, ofloxacin, norfloxacin, ampicillin, cefotaxime, ceftazidime, gentamicin and streptomycin, 5 (55.6%) to sulphamethoxazole-trimethoprim, 7 (77.8%) to amoxicillin-clavulanic acid and aztreonam, 6 (66.7%) to nitrofurantoin and 8 (88.9%) to tetracycline. All the isolates were resistant to ≥ 5 classes of antibacterial agents. Mean multiple antibacterial indexes of the isolates were 0.68 (range 0.79 - 1.00). Apparently-healthy/asymptomatic adults in Ankpa North-central Nigeria, are potential reservoirs and disseminators of multi- and extensive-drug resistant salmonellae.

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Section: Introductionmentioning

confidence: 99%

Generic Salmonella in Asymptomatic Adult Volunteers: Occurrence, Antibiogram, Extended-Spectrum β-Lactamase Production and Carbapenem Resistance

et al. 2019

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“…Production systems that cause continuous exposure to salmonella are usually intensive [ 42 , 43 ] but in more extensive systems the animals may be exposed to environmental bacteria, for example where they are gathered at night or in the milking kraal. The prevalence of salmonella isolated from mesenteric lymph nodes from healthy cattle slaughtered in an abattoir in north-east Nigeria was 61% [ 44 ], although the authors remark that this was probably an over-estimation because of the stress animals had been subjected to before being culled. Nevertheless, salmonella can be expected to circulate in smallholder farming systems in Africa, which the current results support, and measures to prevent exposure of the animals to salmonella from other herds and/or the environment would be expected to reduce the prevalence.…”

Section: Discussionmentioning

confidence: 99%

Biosecurity aspects of cattle production in Western Uganda, and associations with seroprevalence of brucellosis, salmonellosis and bovine viral diarrhoea

et al. 2017

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BackgroundMany low-income countries have a human population with a high number of cattle owners depending on their livestock for food and income. Infectious diseases threaten the health and production of cattle, affecting both the farmers and their families as well as other actors in often informal value chains. Many infectious diseases can be prevented by good biosecurity. The objectives of this study were to describe herd management and biosecurity routines with potential impact on the prevalence of infectious diseases, and to estimate the burden of infectious diseases in Ugandan cattle herds, using the seroprevalence of three model infections.ResultsFarmer interviews (n = 144) showed that biosecurity measures are rarely practised. Visitors’ hand-wash was used by 14%, cleaning of boots or feet by 4 and 79% put new cattle directly into the herd. During the 12 months preceding the interviews, 51% of farmers had cattle that died and 31% had noticed abortions among their cows. Interestingly, 72% were satisfied with the health status of their cattle during the same time period. The prevalence (95% CI) of farms with at least one seropositive animal was 16.7% (11.0;23.8), 23.6% (16.9;31.4), and 53.4% (45.0;61.8) for brucella, salmonella and BVD, respectively.A poisson regression model suggested that having employees looking after the cattle, sharing pasture with other herds, and a higher number of dead cattle were associated with a herd being positive to an increasing number of the diseases. An additive bayesian network model with biosecurity variables and a variable for the number of diseases the herd was positive to resulted in three separate directed acyclic graphs which illustrate how herd characteristics can be grouped together. This model associated the smallest herd size with herds positive to a decreasing number of diseases and having fewer employees.ConclusionThere is potential for improvement of biosecurity practices in Ugandan cattle production. Salmonella, brucella and BVD were prevalent in cattle herds in the study area and these infections are, to some extent, associated with farm management practices.Electronic supplementary materialThe online version of this article (10.1186/s12917-017-1306-y) contains supplementary material, which is available to authorized users.

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“…One sample each was collected per slaughtered animal. Samples were collected aseptically from the slaughtered ruminants as previously described [29].…”

Section: Sample Collectionmentioning

confidence: 99%

“…In addition, there is insufficient and neglected participation of concern policy makers in the control of environmental resources in the developing countries [28]. Furthermore, multi-drug resistant Salmonella has been documented from different food animals slaughtered for human consumption at abattoir [29]. This study aimed at determining the isolation rate and antimicrobial susceptibility profiles of Salmonella species from cattle and small ruminants slaughtered for human consumption at the two major abattoirs in Ilorin, Nigeria.…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial profiles of Salmonella species isolated from ruminants slaughtered at the two major abattoirs in Ilorin, Nigeria

Babatunde

Ahmed

Shuaib

et al. 2022

Microbes and Infectious Diseases

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Background: Foodborne illness due to the genus Salmonella is one of the major challenges affecting public health worldwide and a threat to socioeconomic activities especially in the developing countries. The present study was carried out to determine the isolation rate and antimicrobial susceptibility profiles of Salmonella species from ruminants slaughtered for human consumption at the two major abattoirs in Ilorin, Kwara State. Methods: Between November, 2019 and February, 2020, a total 500 samples were collected from the two major abattoirs in Ilorin metropolis (cattle, n = 240; goat, n = 260). Salmonella species were isolated and identified using standard bacteriological techniques. The isolates were subjected antimicrobial susceptibility test using Kirby Bauer disk diffusion assay. Results: 20 (4 %) Salmonella isolates were obtained, there was no significant statistical difference between the isolation rates from cattle (3.75 %) and the small ruminant (4.23 %). Varying degree of resistance patterns were obtained with high proportion of the isolates (> 60 %) displaying resistance to penicillin and cephalosporin tested while low resistant phenotypes (5 %) were observed against quinolones. The isolates were pan-susceptible to gentamicin. Conclusion:The study documented multidrug resistant Salmonella isolates from ruminants slaughtered for human consumption. It is recommended that further studies to characterize the isolates will assist in recommending the appropriate control strategies to prevent the transmission of resistant Salmonella strains to human via food chain.

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Prevalence and antimicrobial resistance profiles of Salmonella isolates in apparently healthy slaughtered food animals at Maiduguri central abattoir, Nigeria

Cited by 8 publications

References 24 publications

Generic Salmonella in Asymptomatic Adult Volunteers: Occurrence, Antibiogram, Extended-Spectrum β-Lactamase Production and Carbapenem Resistance

Generic Salmonella in Asymptomatic Adult Volunteers: Occurrence, Antibiogram, Extended-Spectrum β-Lactamase Production and Carbapenem Resistance

Biosecurity aspects of cattle production in Western Uganda, and associations with seroprevalence of brucellosis, salmonellosis and bovine viral diarrhoea

Antimicrobial profiles of Salmonella species isolated from ruminants slaughtered at the two major abattoirs in Ilorin, Nigeria

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