Prevalence and Antibiotic Susceptibility Pattern of Staphylococcus aureus isolated from Blood Culture in a Teritiary Care Centre

Abstract

Introduction: Bloodstream infections (BSIs) are associated with significant patient morbidity and mortality. Staphylococcus aureus (S. aureus) is a leading cause of bacteremia. Methicillin resistant Staphylococcus aureus (MRSA) is problematic, as the therapeutic outcome of MRSA infections is much worse compared to methicillin sensitive Staphylococcus aureus (MSSA). Aim: To determine the prevalence &antibiotic susceptibility pattern of Staphylococcus aureus strains isolated from blood culture. Methodology: This study was carried out from July 2016 to December 2016 in which 982 blood culture bottles were processed by automated blood culture system. A total of 161 strains of S. aureus isolated, were identified by standard biochemical methods. Antibiotic susceptibility testing was performed by Kirby Bauer Disk Diffusion method. Methicillin resistance was detected using cefoxitin (30 µg) disc.