Prevalence and antibiogram of Pseudomonas aeruginosa in Chronic Suppurative Otitis Media (CSOM)

Soumya, Swaminathan

doi:10.18535/jmscr/v6i2.156

Cited by 2 publications

(2 citation statements)

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“…Ciprofloxacin displayed a substantial sensitivity rate of 90.91%, and Amoxicillin-clavulanic acid had a lower sensitivity rate of 77.27%. In agreement, Soumya et al [16] revealed that for Pseudomonas aeruginosa, penicillin, piperacillin, and tazobactam were the most effective antibiotics. On the other hand, Kombade et al [17] These findings suggest that Amikacin, Ceftriaxone, Gentamicin, Imipenem, and Vancomycin exhibited varying degrees of effectiveness against S. aureus strains, while Azithromycin and Colistin showed no sensitivity.…”

Section: Discussionmentioning

confidence: 54%

“…Out of the total 100 samples, 6 samples [6%] showed no growth. Candida, E. coli, S. aureus, Pseudomonas aeruginosa, and Klebsiella pneumoniae were detected in 16% [16], 18% [18], 26% [26], 22% [22], and 12% [12] of cases, respectively. In agreement, Sah et al [6] noted that, it was found that Staphylococcus aureus [42.24%] was the most common bacterium isolated in the research, followed by Pseudomonas aeruginosa [28.44%], Klebsiella pneumoniae Sensitivity to amikacin was observed in 60% of the included patients.…”

Section: Discussionmentioning

confidence: 99%

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Current Microbiological Profile and Antibiotic Sensitivity Pattern in Chronic Suppurative Otitis Media in the Post- Antibiotic Era

Agwa,

Mohamed,

Abd El Galil

et al. 2024

International Journal of Medical Arts

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Article informationBackground: Whatever the cause or pathophysiology, middle ear inflammation is known as chronic suppurative otitis media [CSOM].Because CSOM is resistant to local medicines, culture tests are regarded as the gold standard for identifying the causative agents. The aim of the work:This study aims to detect microbiological profile [Bacteria and fungi] and antibiotic sensitivity pattern [For bacterial isolates] in CSOM. Patients and Methods:This was a prospective study conducted on 100 patients with chronic suppurative otitis media who attended in the outpatient department at Al-Azhar university Hospitals from May 2022 to Feb 2023. Microbiological cultures and antibiotic susceptibility testing were performed on ear discharge samples collected from the study participants. Results:The most predominant organism causing CSOM among aerobic bacteria was S. aureus, followed by Pseudomonas Aeruginosa, E. coli and Klebsiella Pneumoniae respectively. The fungal isolate was Candida species. Ciprofloxacin and Colistin were the best medications for treating Pseudomonas aeruginosa. Ciprofloxacin and Vancomycin were effective antibiotics for S. aureus. Amikacin and colistin were the most effective antibiotics for Klebsiella Pneumoniae. Colistin and Imipenem were the most effective antibiotics for E. coli. Conclusion:Understanding the microorganisms and drug sensitivity pattern that cause CSOM and selecting appropriate antibiotics based on susceptibility testing can direct the course of therapy and minimize intracranial and extracranial problems associated with the illness.

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Section: Discussionmentioning

confidence: 54%

Section: Discussionmentioning

confidence: 99%

Current Microbiological Profile and Antibiotic Sensitivity Pattern in Chronic Suppurative Otitis Media in the Post- Antibiotic Era

Agwa,

Mohamed,

Abd El Galil

et al. 2024

International Journal of Medical Arts

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Clinico-bacteriological and antibiotic drug resistance profile of chronic suppurative otitis media at a tertiary care hospital in Western Rajasthan

Kombade

Kaur

Patro

et al. 2021

Journal of Family Medicine and Primary Care

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Background: Chronic suppurative otitis media (CSOM) is a major cause of hearing disability and morbidity in poor socioeconomic developing countries with prevalence of 4%. Indiscriminate use of antibiotics and poor follow up of patients has resulted in treatment failure, emergence of resistant strains, super infection, intra-cranial and extra-cranial complications in CSOM patients. Staphylococcus aureus, P. aeruginosa, Proteus spp. and Klebsiella spp. are most common organisms causing infection. Knowledge of microbial profile and susceptibility pattern is essential for efficacious treatment of this disorder. Objective: To determine the clinico-bacteriological profile of CSOM, to analyze the susceptibility pattern of various antibiotics and to evaluate the in vitro efficacy of aminoglycosides over fluoroquinolones against the aerobic bacterial isolates from CSOM. Methods: We studied 153 clinically suspected CSOM cases from March 2018 to October 2018 in Microbiology and Otorhinolaryngology department. The ear swabs were aerobically cultured and identification of the isolate was done by standard bacteriological methods. Results: Safe type CSOM was a major cause of disease. Moderate (35.3%) and mild degree (32.7%) of hearing loss was seen in most of the CSOM cases. The culture positivity rate was 82.4% and the most common isolate was P. aeruginosa (55.8%) followed by S. aureus (27.5%). P. aeruginosa, A. baumannii and Enterobacteriaceae spp. showed high sensitivity to colistin, piperacillin-tazobactam, ceftazidime-tazobactam and good sensitivity for cefepime and amikacin; 33.3% S. aureus isolates were Methicillin-resistant which was sensitive to gentamicin, vancomycin and linezolid. Conclusion: Knowledge of the spectrum of microorganisms causing ear discharge is important for effective treatment.

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Prevalence and antibiogram of Pseudomonas aeruginosa in Chronic Suppurative Otitis Media (CSOM)

Abstract: Background: CSOM is the most common notorious infection seen in developing countries which has led to a number of serious life threatening complications. The most common organism isolated in CSOM is

Cited by 2 publications

References 9 publications

Current Microbiological Profile and Antibiotic Sensitivity Pattern in Chronic Suppurative Otitis Media in the Post- Antibiotic Era

Current Microbiological Profile and Antibiotic Sensitivity Pattern in Chronic Suppurative Otitis Media in the Post- Antibiotic Era

Clinico-bacteriological and antibiotic drug resistance profile of chronic suppurative otitis media at a tertiary care hospital in Western Rajasthan

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