Prevalence and Antibiogram of Acinetobacter Species Isolated from Various Clinical Samples in a Tertiary Care Hospital

Rajkumari, Sanjana; Pradhan, Shanti; Sharma, Damodar; Jha, Brajesh Kumar

doi:10.3126/jcmsn.v16i1.28224

Cited by 4 publications

(9 citation statements)

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“…were isolate in 31 samples whereas sputum 45.20%, ET 38.70% pleural fluid 9.60% BAL 6.50%. Which correlate with the studies of Rajkumari S et al 12 who reported the isolated Acinetobacter spp. were maximum from sputum 31.88% followed by ET 61.66%.…”

Section: Discussionsupporting

confidence: 91%

“…identify in out of culture positive 11.49% as resulted conducted by Rajkumari S et al and Devi PG et al in 2015 observed in their study that out of 452 patients 18.14% were isolate Acinetobacter infection in ICU. 7,12 Prasad A et al who also reported 15.68%. 10 In our study out of total samples were culture positive in various clinical samples Acinetobacter spp.…”

Section: Discussionmentioning

confidence: 95%

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Isolation of Acinetobacter Spp. and its antimicrobial resistance pattern in all lower respiratory samples from ICU

Sharma¹,

Rani

Farooq³

et al. 2022

IJMMTD

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. are found in moist natural environment and hospital settings. In ICU . is the most common cause of Respiratory tract infection. . has evolved from a minor infection to one of the most virulent and multidrug-resistant, pathogens in intensive care units. Overuses of the antibiotics patients drug resistant pattern are increase and immune compromise patient are not recover early. This research will help in better infection control and a better knowledge of antibiotic resistance patterns in our area. The aim and objective of this study is isolation of . and its antimicrobial resistance pattern in all lower respiratory samples from ICU. All lower respiratory samples were collected (Sputum, BAL, ET etc.) samples was inoculated on MacConkey and blood agar. At 37 degrees Celsius, culture plates were incubated aerobically for 24 hours. Gram staining and biochemical test were used to identify the Acinetobacter species. All species was isolate further processed on the basis of AST by automated through vitek2 compact.Among 151 samples, 71 (47.01%) were culture positive. was isolated in 31 (43.66%). The number and percentage of in various clinical sample were sputum 14 (45.20%), ET 12 (38.70%), pleural fluid 3 (9.60%), BAL 2 (6.50%). The strains showed maximum resistance to Ampicillin (100%) and pipracillinetazobactum (94.0%), Ceftazidime (86%) followed by gentamycin (77%), Ciprofloxacin (72%). All the strains were sensitive to colistin and Polymyxin B (100%).The rise of resistant strains has resulted in fewer treatment choices. Because of the limited therapeutic options, infection prevention and control methods, including not only standard measures but also antibiotic management strategies in the ICU, are important.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 95%

Isolation of Acinetobacter Spp. and its antimicrobial resistance pattern in all lower respiratory samples from ICU

Sharma¹,

Rani

Farooq³

et al. 2022

IJMMTD

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“…Our observation also showed a higher percentage of multidrug resistant bacteria than the findings of India (37.1%) [4] and Nepal (51.03%) [18]. The rate of multidrug resistant Acinetobacter spp.has been reported as 57% to 62.2%, 71.6% and 80.4% from Bangladesh, India and Nepal respectively [30,6,31,22], which are lower than our findings (98.9%). Contrary, a study from Ghana reported the prevalence of multidrug resistant Acinetobacter spp.…”

Section: Discussioncontrasting

confidence: 75%

“…with a sensitivity of 93.3%. Previously conducted studies from Bangladesh (sensitivity 95.1%) [6], Nepal (sensitivity 100%) [22], and Turkey (97.8%) [23] also reported colistin as the most effective drug against this bacterial species. One study from Nepal [18] reported piperacillin-tazobactam as the most effective drug against Acinetobacter spp.…”

Section: Discussionmentioning

confidence: 87%

Antimicrobial susceptibility patterns of bacterial isolates from routine clinical specimens of a tertiary hospital in Bangladesh

Hossain

Begum

2021

IMC Journal of Medical Science

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Background and objectives: To prevent the emergence and spreading of antimicrobial resistance, especially multidrug resistance in pathogenic bacteria, the selection of appropriate antibiotics is a prerequisite for the effective treatment of infection.This study aimed to analyze the prevalence and antimicrobial resistance patterns of bacterial isolates from various clinical samples in a tertiary care hospital. Methods: This study was conducted at a teaching hospital of Dhaka city, Bangladesh from January 2020 to March 2021. The results of culture and antimicrobial susceptibility of bacterial isolates from various clinical samples were collected and analysed. Identification of bacteria and antimicrobial susceptibility test were performed according to the standard methods. Results: A total of 1277 bacterial isolates was analyzed. Of them, 1072 (83.95%) were Gram-negative, and 205 (16.05%) were Gram-positive bacteria. Among the isolates, Escherichia coli (n=576), Enterobacter spp. (n=150), Klebsiella spp. (n=140), and Staphylococcus aureus (n=117) were predominant.The Enterobacteriaceae showed higher resistance to cephradine (94.3%) and cefuroxime (76.7%), whereas least resistant to imipenem (10.1%) and meropenem (14.8%). Pseudomonas spp. was highly resistant to ceftriaxone (80.2%), and colistin (70.8%), whereas least resistant to piperacillin-tazobactam (15.1%). Colistin was the most effective agent (resistance 6.7%) against Acinetobacter spp. Linezolid (resistance 1%) and vancomycin (resistance 2%) were highly effective against Gram-positive bacteria. Among the Staphylococcus aureus, 95.7% were methicillin-resistant (MRSA). A total of 889 (69.6%) bacterial isolates were identified as multidrug resistant. Multidrug resistance was more prevalent in Gram-positive isolates (79.5%) than that of Gram-negative bacteria (67.7%). Furthermore, 7.5% of Gram-negative bacterial isolates were resistant to all seven classes of antibiotics tested. Conclusions: This study revealed presence of high rate of resistance to several antimicrobial agents in bacteria isolated from various clinical samples.The findings would help healthcare professionals to select appropriate antibiotics for the effective treatment of infections and to develop antibiotic stewardship protocol. IMC J Med Sci 2022; 16(1): 005 *Correspondence: M. Mahboob Hossain, Microbiology Program, Department of Mathematics and Natural Sciences (MNS), BRAC University, 66 Mohakhali, Dhaka 1212. E-mail: mmhossain@bracu.ac.bd

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“…As a result of increasing antibiotic pressure in hospitals, new strains with higher antibiotic resistance emerge and they replace the previous strains. While methicillin resistance in S. aureus is less in countries like Norway and Sweden (1%), Netherlands (2%) and Canada (5-10%), it is 25-50% in the United States, 54% in Portugal and 43%-58% in Italy (7). High prevalence of MRSA is an emerging problem in India.…”

Section: Issn: 2319-7706 Volume 8 Number 01 (2019)mentioning

confidence: 99%

Changing Trends in Resistance Pattern of Methicillin Resistant Staphylococcus aureus in Burn Patients

More¹,

Kauser²,

Kandle³

et al. 2019

Int.J.Curr.Microbiol.App.Sci

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Prevalence and Antibiogram of Acinetobacter Species Isolated from Various Clinical Samples in a Tertiary Care Hospital

Cited by 4 publications

References 0 publications

Isolation of Acinetobacter Spp. and its antimicrobial resistance pattern in all lower respiratory samples from ICU

Isolation of Acinetobacter Spp. and its antimicrobial resistance pattern in all lower respiratory samples from ICU

Antimicrobial susceptibility patterns of bacterial isolates from routine clinical specimens of a tertiary hospital in Bangladesh

Changing Trends in Resistance Pattern of Methicillin Resistant Staphylococcus aureus in Burn Patients

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