2010
DOI: 10.1016/j.mehy.2009.11.044
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Pretty painful: Why does tooth bleaching hurt?

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Cited by 196 publications
(149 citation statements)
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“…Since the afferent fibers of primary dental pulp contain TRPA1, it is possible that direct TRPA1 activation of nerve fibers is involved in the pain caused by tooth bleaching. 14 The mechanisms responsible for tooth sensitivity after bleaching have not been fully elucidated; however, some inflammatory mediators may play an important role. 1,15 These effects have commonly been reported in association with bleaching techniques and different peroxide concentrations, although inoffice whitening products cause greater sensitivity than at-home bleaching gels.…”
Section: Introductionmentioning
confidence: 99%
“…Since the afferent fibers of primary dental pulp contain TRPA1, it is possible that direct TRPA1 activation of nerve fibers is involved in the pain caused by tooth bleaching. 14 The mechanisms responsible for tooth sensitivity after bleaching have not been fully elucidated; however, some inflammatory mediators may play an important role. 1,15 These effects have commonly been reported in association with bleaching techniques and different peroxide concentrations, although inoffice whitening products cause greater sensitivity than at-home bleaching gels.…”
Section: Introductionmentioning
confidence: 99%
“…Although the etiology of this side effect has not yet been fully established, it seems that it results from the peroxide penetrating through enamel and dentin and into the pulp during tooth whitening. 24,25 Within five to 15 minutes after application of a bleaching gel, peroxide penetrates to the pulp, where it irritates nerves and essentially produces a reversible pulpitis. [26][27][28] Further proof of this passage of peroxide is found in the research that showed color changes in dentin next to the pulp as fast as it occurs next to the dentin-enamel junction.…”
Section: Discussionmentioning
confidence: 99%
“…27 On the other hand, the study of Browning and others 26 reported that cold stimulus was the most painful stimulus, followed by gingival sensitivity and then sensitivity due to hot stimuli in patients using 10% carbamide peroxide with potassium nitrate and sodium fluoride as desensitizing agents.…”
Section: Tooth Sensitivity Evaluationmentioning
confidence: 99%