Preterm premature rupture of membranes and neonatal outcome prior to 34 weeks of gestation

Tanir, H. Mete; Şener, Turgay; Tekin, Neslihan; Akşit, Arif; Ardic, Nazan

doi:10.1016/s0020-7292(03)00125-5

Cited by 52 publications

(41 citation statements)

References 18 publications

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“…We reported a case fatality rate of 3.5%; it is comparable with another similar study that reported a death rate of 4.6% [9]. Almost all neonates were premature (n = 14), as mentioned and reported by other published studies [40]. This is a retrospective chart review; we were not able to assess all the variables and were limited by the completeness of documentation by the treating physician.…”

Section: Discussionsupporting

confidence: 83%

Neonatal sepsis following prolonged rupture of membranes in a tertiary care hospital in Karachi, Pakistan

Alam

Saleem

Shaikh

et al. 2014

J Infect Dev Ctries

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Introduction: Prolonged rupture of membrane (PROM) is an important risk factor for early onset neonatal sepsis (EONS), which is associated with increased neonatal morbidity and mortality. We reported the incidence and associated risk factors of PROM for culture-proven EONS. Methodology:The medical records of all neonates born at Aga Khan University, Karachi over a period of five years (2007)(2008)(2009)(2010)(2011) with PROM (> 18 hours) were reviewed. Data about maternal and neonatal risk factors for EONS was collected and adjusted logistic regression (AOR) analysis was applied. Results:Incidence of PROM in this neonatal birth cohort was 27/1,000 live births. A total of 17 (4%) cases with blood-culture proven bacterial sepsis were identified within 72 hours of birth. Klebsiella pneumonia (n = 5; 29%) and Pseudomonas aeruginosa (n = 4; 24%) were the commonest isolates followed by group B Streptococcus (n = 3; 18%) and Escherichia coli (n = 2; 12%). Maternal fever (p = <0.001; AOR, 36.6), chorioamnionitis (p < 0.001; AOR, 4.1), PROM > 48 hr. (p < 0.001; AOR, 8.2), neonatal prematurity < 34 weeks (p < 0.001; AOR, 4.1) and low birth weight < 1,500 grams (p 0.001; AOR, 9.8) along with neonatal thrombocytopenia and raised CRP were found to be independent risk factors associated with culture-proven EONS in PROM. Conclusions: Preventive measures should focus on recognition of these high-risk infants with prompt laboratory screening for sepsis and early institution of empirical antibiotic based on local data. Such approaches would be a safe and cost-effective strategy, especially in developing countries.

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Section: Discussionsupporting

confidence: 83%

Neonatal sepsis following prolonged rupture of membranes in a tertiary care hospital in Karachi, Pakistan

Alam

Saleem

Shaikh

et al. 2014

J Infect Dev Ctries

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“…Assim como no presente estudo, outras pesquisas observaram que as mães que foram internadas na gestação têm maior risco de nascimento pré-termo 41,42 . Este fator sugere relação com todos os agravos de risco que também foram detectados.…”

Section: Discussionunclassified

Fatores de risco para nascimentos pré-termo em Londrina, Paraná, Brasil

et al. 2009

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IntroduçãoSegundo a Classificação Internacional de Doenças 1 , nascimento pré-termo é o que ocorre com menos de 37 semanas de gestação. Essas crianças têm um risco elevado de adoecer e morrer em razão de seu incompleto desenvolvimento fetal e maior suscetibilidade às infecções, complicadas pela manipulação e grande período de permanência nas unidades neonatais. Muitos evoluem com seqüelas neurológicas, oftalmoló-gicas ou pulmonares 2 .Os nascimentos pré-termo são classificados em dois tipos clínicos: espontâneos e por indicação médica. Os espontâneos são subdivididos em dois tipos: o primeiro denominado trabalho de parto prematuro de causa idiopáti-ca, caracteriza-se por contrações uterinas que progridem com ou sem ruptura das membranas amnióticas e o segundo quando a ruptura das membranas amnióticas antecede o trabalho de parto. O nascimento pré-termo por indicação médica ocorre quando por problemas da mãe ou do feto há contra-indicação da continuidade da gravidez 3,4,5 .O limitado conhecimento da etiologia do trabalho de parto prematuro e da ruptura prematura de membranas juntamente com a não intervenção precoce nos problemas maternos e fetais são apontados como fatores que dificultam a redução da freqüência de nascimentos pré-termo 6 .ARTIGO ARTICLE Silva AMR et al.

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“…Perinatal mortality after PROM near term ia associated with infection and in preterm due to RDS. Perinatal mortality is 19% according to Tanir et al 38 .…”

Section: Perinatal Mortalitymentioning

confidence: 99%

Maternal and Foetal Outcome in Premature Rupture of Membranes

Patil¹,

Patil²

2014

IOSRJDMS

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Preterm premature rupture of membranes and neonatal outcome prior to 34 weeks of gestation

Abstract: Neonatal outcome was mainly affected by prematurity rather than by preterm premature rupture of membranes.

Cited by 52 publications

References 18 publications

Neonatal sepsis following prolonged rupture of membranes in a tertiary care hospital in Karachi, Pakistan

Neonatal sepsis following prolonged rupture of membranes in a tertiary care hospital in Karachi, Pakistan

Fatores de risco para nascimentos pré-termo em Londrina, Paraná, Brasil

Maternal and Foetal Outcome in Premature Rupture of Membranes

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