Preterm infants: is prophylactic surfactant therapy and early vitamin A supplementation the way ahead?

Sharma, Monika

doi:10.1016/s0377-1237(11)60001-4

Cited by 2 publications

(3 citation statements)

References 17 publications

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“…4 The incidence decreases with advancing gestational age, about 50% babies born at 26-28 weeks to about 25% at 30-31 weeks. 5 The risk for development of RDS increases with maternal diabetes, multiple births, asphyxia, cord stress and prior history of siblings born with RDS, secondary to oxygen toxicity, mechanical ventilation, CDH and pulmonary hypoplasia. 6 The incidence is highest in preterm male and white infants.…”

Section: Introductionmentioning

confidence: 99%

“…The respiratory rate may increase to more than 100 breaths per minute and baby becomes cyanotic. 5 Respiratory distress in the newborn is recognized as one or more signs of increased work of breathing, such as tachypnea, nasal flaring, chest retractions or grunting. [6][7][8] It is uncommon to develop hyaline membrane disease if the infant breaths normally for 6-8 hours.…”

Section: Introductionmentioning

confidence: 99%

“…The diagnosis is made by the clinical picture and the chest X-ray, which demonstrates decreased lung volumes, a small, discrete, uniform infiltrate that involves all lobes of the lung (described as a "ground glass" appearance), and the presence of air-bronchograms. 5 Most cases of infant respiratory distress syndrome can be prevented if mothers are given glucocorticoids during the antenatal period. The American college of obstetricians and gynecologists (ACOG) have recommended antenatal glucocorticoid treatment for women at risk for preterm delivery prior to 34 weeks of gestation.…”

Section: Introductionmentioning

confidence: 99%

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Outcome of pre-term babies born in tertiary care institute

Murthy

Saravanan

2019

Int J Contemp Pediatr

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Background: Preterm babies’ survival has improved with advances in neonatology care in this era. Even with advances in treatments, there is still morbidity and mortality among preterm. The objective of this study was to know the incidence of prematurity and complications seen in them.Methods: A cross sectional study was conducted on all preterm babies born in Sapthagiri Institute of Medical Sciences, Bangalore, over period of one year from 1st August 2017 to July 2018.Results: Out of 500 babies born, 110 babies had RDS, among 110 babies 85 cases were preterm RDS babies included in study. Majority were males 55 (64.5%) and females 30 (35.2%). The gestational age group was maximum in the 28-32weeks,the most common morbidity noted was sepsis (77.7%) and RDS (22%). Death was 9(10.5%) only 4(4.7%) needed intervention in the form of CPAP.Conclusions: The study concluded that males were commonly affected by respiratory distress syndrome, sepsis was a common cause for morbidity and mortality. Inspite of advances in neonatology sepsis continues to be a leading cause of death. Proper hand cleansing has to be emphasized and reinforced to prevent sepsis in NICU. The best possible attempts to delay preterm delivery have to be followed. One should have a high index of suspicion and low threshold to treat sepsis in preterm.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Outcome of pre-term babies born in tertiary care institute

Murthy

Saravanan

2019

Int J Contemp Pediatr

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Noninvasive Respiratory Support and Feeding in the Neonate

2017

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Background Preterm neonates are at risk for respiratory illness including respiratory distress syndrome (RDS) and bronchopulmonary dysplasia (BPD). Recent advancements in neonatal medicine have introduced less invasive forms of respiratory support for neonates with RDS and BPD, including continuous positive airway pressure (CPAP) and humidified “high-flow” therapy via nasal cannula (HFNC). There is limited evidence documenting the impact of these respiratory supports on neonatal swallowing function. Objective This article presents the results of a structured literature review that sought to determine the evidence to support the practice of feeding neonates in the neonatal intensive care unit (NICU) by mouth while on CPAP or HFNC. Methods A systematic search of PubMed was completed to identify relevant, peer-reviewed literature reporting original data that addressed the identified objective. Results Five studies were identified that related to oral feeding and/or swallowing while on CPAP or HFNC in neonates. Conclusions Given the limited evidence available to support the practice of feeding neonates in the NICU by mouth while on CPAP or HFNC, and the potential for adverse respiratory events related to the underlying respiratory disease, the authors urge caution with this practice, and highlight the urgent need for further research in this area.

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Preterm infants: is prophylactic surfactant therapy and early vitamin A supplementation the way ahead?

Cited by 2 publications

References 17 publications

Outcome of pre-term babies born in tertiary care institute

Outcome of pre-term babies born in tertiary care institute

Noninvasive Respiratory Support and Feeding in the Neonate

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