Presystolic A wave may predict increased arterial stiffness in asymptomatic individuals

Korkmaz, Levent; Akyüz, Ali Rıza; Gürbak, İsmail; Erkan, Hakan; Dursun, İhsan; Çelık, Şükrü

doi:10.1097/mbp.0000000000000176

Cited by 21 publications

(24 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Original article 1 and impaired LV compliance [9,10]. Considering that PSW may be associated with subclinical LV dysfunction in hypertensive patients, we hypothesized that PSW could reflect subclinical LV dysfunction.…”

Section: Introductionmentioning

confidence: 99%

The relationship between presystolic wave and subclinical left ventricular dysfunction in asymptomatic hypertensive patients

Akyüz

Turhan

Gürbak

et al. 2016

Blood Pressure Monitoring

Self Cite

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

The relationship between presystolic wave and subclinical left ventricular dysfunction in asymptomatic hypertensive patients

Akyüz

Turhan

Gürbak

et al. 2016

Blood Pressure Monitoring

Self Cite

View full text Add to dashboard Cite

show abstract

“…15 PSW may theoretically be associated with poor LV compliance and increased LV stiffness. 16,17 Given the hypothetical link between PSW and subclinical LVD in type 2 DM, we theorized that PSW may be associated with subclinical LVD in patients with type 2 DM.…”

Section: Introductionmentioning

confidence: 99%

Presystolic Wave is Associated with Subclinical Left Ventricular Dysfunction Assessed by Myocardial Performance Index in Type 2 Diabetes Mellitus

Kul

Dursun

Ayhan³

et al. 2019

Arquivos Brasileiros De Cardiologia

Self Cite

View full text Add to dashboard Cite

BackgroundMyocardial performance index (MPI), demonstrates both systolic and diastolic functions of the left ventricle. Presystolic wave (PSW) is frequently detected on Doppler examination of the left ventricular outflow tract and possible mechanism of PSW is impaired LV compliance and left ventricular stiffness.ObjectiveTo investigate the relationship between PSW and MPI in type 2 diabetic patients.MethodA total of 129 type 2 diabetic patients were included in this study. Patients were divided into two groups according to the presence of PSW on Doppler echocardiography. There were 90 patients (38 male, mean age 57.77 ± 10.91 years) in the PSW-positive group and 39 patients (13 male; mean age: 55.31 ± 11.29 years) in the PSW-negative group. The p values of < 0.05 were considered statistically significant.ResultsMPI was higher in PSW- positive group (0.63 ± 0.17vs 0.52 ± 0.13, p < 0.001). In addition, subclinical left ventricle dysfunction (LVD) was higher in the PSW- positive group (p = 0.029). Univariate analysis showed that the presence of PSW associated with abnormal MPI (p = 0.031). Pearson correlation analysis showed that PSW velocity correlated with MPI (r: 0.286, p = 0.006).ConclusionPresence of the PSW on Doppler examination was associated with subclinical LV dysfunction in patients with DM type 2. This easy-to-perform echocardiographic parameter may be related to subclinical LVD among patients with type 2 DM.

show abstract

“…Akyuz et al found that PSW presence and increased PSW velocity in hypertensive patients were related to subclinical left ventricle dysfunction. Korkmaz et al reported a greater PSW velocity among patients with abnormal CAVI (cardio ankle vascular index) than those without. We demonstrated in this study that increased CIMT in patients with PSW than those without PSW.…”

Section: Discussionmentioning

confidence: 98%

“…The Doppler interrogation of the left ventricular outflow tract (LVOT) commonly includes a presystolic wave (PSW), the possible mechanism of which is left ventricular stiffness and impaired LV compliance . Its prevalence and clinical significance, however, remain to be determined.…”

Section: Introductionmentioning

confidence: 99%

Presystolic wave is associated with carotid intima media thickness

et al. 2018

Self Cite

View full text Add to dashboard Cite

Introduction Carotid intima media thickness (CIMT), a direct marker of atherosclerosis, has emerged as a promising means for cardiovascular risk evaluation. Presystolic wave (PSW) is commonly detected by the Doppler interrogation of the left ventricular outflow tract (LVOT). It is thought to be a result of a stiff left ventricle and impaired LV compliance. Herein, we aimed to investigate a possible association between carotid intima media thickness, an atherosclerotic marker, and PSW. Method We prospectively enrolled 282 patients divided into two groups based on the presence of PSW: 221 (89F; mean age: 49.3 ± 11.5 years) had PSW on Doppler examination while 61 patients (32F; mean age: 46.4 ± 10.3 years) did not. Both groups were compared with respect to demographic, clinical properties, and CIMT. Results Both groups had comparable age, body mass index, and diabetes mellitus, hypertension, dyslipidemia, smoking, and family history for coronary heart disease. PSW‐positive group had significantly higher CIMT (PSW‐positive: 0.59 ± 0.22 mm vs PSW‐negative: 0.42 ± 0.11 mm; P < 0.001) than PSW‐negative group. Multivariate analysis showed that the independent predictors of increased CIMT were age (95% CI; 1.044–1.101, P < 0.001), dyslipidemia (95% CI; 0.147–0.664, P = 0.002), and the presence of PSW (95% CI; 2.168–7.836, P < 0.001).Correlation analysis showed that PSW velocity is correlated with increased CIMT in PSW‐positive group (r: 0.418, P < 0.001). Conclusion Assessment of PSW on TTE is easy and feasible method. Presence of PSW and increased PSW velocity on TTE might provide information that we should be careful in terms of subclinical atherosclerosis.

show abstract

Presystolic A wave may predict increased arterial stiffness in asymptomatic individuals

Abstract: Assessment of presystolic A wave on echocardiography examination may provide important information on the vascular function, which has a prognostic impact.

Cited by 21 publications

References 21 publications

The relationship between presystolic wave and subclinical left ventricular dysfunction in asymptomatic hypertensive patients

The relationship between presystolic wave and subclinical left ventricular dysfunction in asymptomatic hypertensive patients

Presystolic Wave is Associated with Subclinical Left Ventricular Dysfunction Assessed by Myocardial Performance Index in Type 2 Diabetes Mellitus

Presystolic wave is associated with carotid intima media thickness

Contact Info

Product

Resources

About