Pressurized planar electrochromatography

Dzido, Tadeusz H.; Płocharz, Paweł W.; Chomicki, Adam; Hałka-Grysińska, Aneta; Polak, Beata

doi:10.1016/j.chroma.2011.03.014

Cited by 27 publications

(23 citation statements)

References 35 publications

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“…Within the last ten years, due to the development of technology, there has been a significant breakthrough in synthesizing monolithic columns (see Table 2). In comparison to applications with packed columns, there are almost two times more papers about the use of monolithic capillaries in pCEC drug analysis [29][30][31][32][33][34][35][36][37][38][39][40][41][42].…”

Section: Applications Of Pcec With Monolithic Columnsmentioning

confidence: 99%

“…Herein, researchers have investigated molecularly imprinted polymers [29,35], sulfonated and cationic stearyl methacrylate [31], methacrylate based [33], phenylaminopropyl silica based [34] columns. Most are proprietary ideas or modifications of ideas of other authors [29][30][31][32][33][34][35][36][37][38][39][40][41][42].…”

Section: Applications Of Pcec With Monolithic Columnsmentioning

confidence: 99%

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An underestimated technique. Does pressurized and pressure-assisted capillary electrochromatography have potential in drug and pharmacological-active compounds analysis?

Trzebiatowski

Gwarda

Dzido

2019

Current Issues in Pharmacy and Medical Sciences

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Pharmaceutical analysis guarantees patient safety all over the world. Thus, continuous development of existing analytical techniques is still very important. Pressurized capillary electrochromatography and pressure-assisted capillary electrochromatography are hybrid separation techniques that combine the selectivity of liquid chromatography and the high separation efficiency of capillary electrophoresis. They use a smaller amount of reagents and samples, hence, reducing the total cost of analysis. Therefore they have found application in a number of pharmaceutical and biomedical analysis. This review article focuses on the use and importance of pressurized and pressure-assisted capillary electrochromatography in pharmaceutical and biomedical analysis, taking into account types of detectors and capillaries used. Despite the fact that pressurized capillary electrochromatography and pressure assisted capillary electrochromatography offer many possibilities and have been available for over a dozen years, they are still underdevelopment and not fully explored.

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Section: Applications Of Pcec With Monolithic Columnsmentioning

confidence: 99%

Section: Applications Of Pcec With Monolithic Columnsmentioning

confidence: 99%

An underestimated technique. Does pressurized and pressure-assisted capillary electrochromatography have potential in drug and pharmacological-active compounds analysis?

Trzebiatowski

Gwarda

Dzido

2019

Current Issues in Pharmacy and Medical Sciences

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“…12 [45,46]. The sample is applied to a prewet layer as spots of bands and quickly mounted in a holder in the overpressured separation chamber.…”

Section: Pressurized Planar Electrochromatographymentioning

confidence: 99%

Instrument platforms for thin-layer chromatography

Bernard-Savary¹,

Poole

2015

Journal of Chromatography A

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“…In the PPEC the mobile phase is also driven into movement by electric field contrary to conventional thin layer chromatography (TLC) where capillary forces are responsible for movement of the mobile phase. Forcing the flow of the mobile phase by electric field provides a number of important advantages of PPEC over TLC [14–30]. First of all the flat profile of the EOF makes the electrochromatographic separations more efficient compared to conventional TLC.…”

Section: Introductionmentioning

confidence: 99%

Influence of the Modifier Type and its Concentration on Electroosmotic Flow of the Mobile Phase in Pressurized Planar Electrochromatography

et al. 2014

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The aim of this work was to find a relationship between electroosmotic flow (EOF) velocity of the mobile phase in pressurized planar electrochromatography (PPEC) and physicochemical properties like zeta potential, dielectric constant, and viscosity of the mobile phase as well as its composition. The study included different types of organic modifiers (acetonitrile, methanol, ethanol, acetone, formamide, N-methylformamide and N,N-dimethylformamide) in the full concentration range. In all experiments, chromatographic glass plates HPTLC RP-18 W from Merck (Darmstadt) were used as a stationary phase. During the study we found that there is no linear correlation between EOF velocity of the mobile phase and single variables such as zeta potential or dielectric constant or viscosity. However, there is quite strong linear correlation between EOF velocity of the mobile phase and variable obtained by multiplying zeta potential of the stationary phase–mobile phase interface, by dielectric constant of the mobile phase solution and dividing by viscosity of the mobile phase. Therefore, it could be concluded that the PPEC system fulfilled the Helmholtz–Smoluchowski equation.

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Pressurized planar electrochromatography

Cited by 27 publications

References 35 publications

An underestimated technique. Does pressurized and pressure-assisted capillary electrochromatography have potential in drug and pharmacological-active compounds analysis?

An underestimated technique. Does pressurized and pressure-assisted capillary electrochromatography have potential in drug and pharmacological-active compounds analysis?

Instrument platforms for thin-layer chromatography

Influence of the Modifier Type and its Concentration on Electroosmotic Flow of the Mobile Phase in Pressurized Planar Electrochromatography

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