Pressurised metered dose inhalers versus all other hand-held inhaler devices to deliver beta-2 agonist bronchodilators for non-acute asthma

Abstract

Pressurised metered dose inhalers versus all other hand-held inhaler devices to deliver beta-2 agonist bronchodilators for non-acute asthma (Review)

Inhaler devices for the treatment of asthma and chronic obstructive airways disease (COPD)

“…43 In addition, no evidence was found to support claims that higher dosing schedules (2:1 or greater) had any clinical advantage over 1:1 dosing.…”

Terapia nebulizada. Año SEPAR

“…Diferentes revisiones sistemáticas han demostrado que los 3 tipos de dispositivos habitualmente utilizados para la administración de broncodilatadores y corticoides inhalados (cartuchos presurizados, inhaladores de polvo seco y nebulizadores) tienen una eficacia similar cuando se utilizan de forma adecuada [2][3][4]6,7 . Sin embargo, la práctica clínica nos demuestra que algunos pacientes, particularmente los de edad avanzada, con limitaciones físicas, mentales, o con enfermedad grave, son incapaces de utilizar correctamente los dispositivos de polvo seco o los cartuchos presurizados 8 .…”

Management of paediatric asthma

“…Nebulised therapy is reserved for severe acute asthma, and the occasional child who has a tantrum whenever the spacer is placed near its face (budesonide is available as a nebulised solution). Since the clinical effect of short acting b 2 -agonists in stable paediatric asthma is independent of the delivery device, 38 personal preference therefore dictates whether terbutaline (available as a pMDI and dry powder breath actuated device) or salbutamol (available as a pMDI, breath actuated MDI, or dry powder breath actuated device) is chosen. Salmeterol is available as a pMDI and dry powder (Accuhaler), whereas formoterol is only available as a dry powder (Turbohaler).…”