Pressure-volume loops: A dynamic approach to the assessment of ventricular function

Foëx, P.; Leone, Bruce J.

doi:10.1016/1053-0770(94)90020-5

Cited by 30 publications

(17 citation statements)

References 77 publications

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“…Our study is extending the association of baPWV with MW. In any given contractile state of the LV, MW has been shown to reflect the myocardial oxygen metabolism and eventually the LV function ( 28 ). We explored not only four components of MW but also other indices of left ventricular systolic function: such as, LVEF, FS, and GLS.…”

Section: Discussionmentioning

confidence: 99%

Impact of Brachial-Ankle Pulse Wave Velocity on Myocardial Work by Non-invasive Left Ventricular Pressure-Strain in Non-hypertensive and Hypertensive Patients With Preserved Left Ventricular Ejection Fraction

Duan

Zhang

Dong

et al. 2022

Front. Cardiovasc. Med.

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ObjectiveData regarding the influence of arterial stiffness on myocardial work (MW) has been scarce. This study was performed to investigate the association between brachial-ankle pulse wave velocity (baPWV) and MW by non-invasive left ventricular pressure–strain in a population of non-hypertensive and hypertensive individuals.MethodsTwo hundred and eight participants (104 hypertensive and 104 non-hypertensive individuals) were prospectively enrolled into the study. All participants underwent conventional echocardiography, as well as 2D speckle-tracking echocardiography to assess MW by non-invasive left ventricular pressure–strain and global longitudinal strain (GLS). baPWV measurements were made at the same day as the echocardiography. Then, participants were categorized according to baPWV tertiles. Correlation between baPWV and MW were analyzed. Predicting ability of baPWV for abnormal WM was analyzed using receiver operating characteristic (ROC) curve.ResultsThe median baPWV from the low to high tertile groups were 1286.5 (1197.5–1343.5), 1490.0 (1444.5–1544.0), and 1803.8(1708.3–1972.0) cm/s, respectively. In simple linear regression analysis, baPWV had a significant positive association with global work index (GWI), global constructed work (GCW), and global wasted work (GWW), and a negative association with global work efficiency (GWE). The association remained significant after adjusting for major confounding factors in multiple linear regression analysis. The areas under the ROC curve of baPWV for predicting abnormal GWI, GCW, GWW, and GWE were 0.653, 0.666, 0.725, and 0.688, respectively (all p < 0.05).ConclusionsBaPWV is significantly associated with all four components of MW using non-invasive left ventricular pressure-strain method in a mixed population of non-hypertensive and hypertensive individuals.

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Section: Discussionmentioning

confidence: 99%

Impact of Brachial-Ankle Pulse Wave Velocity on Myocardial Work by Non-invasive Left Ventricular Pressure-Strain in Non-hypertensive and Hypertensive Patients With Preserved Left Ventricular Ejection Fraction

Duan

Zhang

Dong

et al. 2022

Front. Cardiovasc. Med.

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“…was measured three times during the study, as follows: once before the first series of measurements, again after the pericardium was opened, and then at the end of the experiment. Parallel conductance artefact for both ventricles was determined separately using a single injection of 5 ml of 10 N saline injected into the inferior vena cava by the saline dilution method (Foëx & Leone, 1994). In practice, this repositioning was required in three of the seven pigs before data collection.…”

Section: Conductance Catheter Volume Signalsmentioning

confidence: 99%

Dynamic right and left ventricular interactions in the pig

Pinsky

2020

Experimental Physiology

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I characterized the dynamic factors determining ventricular interdependence with and without the pericardium. I measured right (RV) and left ventricular (LV) pressures and volumes simultaneously using conductance catheters in seven pentobarbitoneanaesthetized open-chested 5-to 7-week-old piglets. I studied these effects during apnoea, inferior vena caval occlusion and rapid partial aortic and pulmonary arterial occlusions. Conductance catheter-defined long-axis regional volumes were assessed to define regional contractile synchrony. Closed-pericardium measures were made from an initial (baseline) volume, then after two 20 ml kg −1 fluid loads followed by an open-pericardium step. Baseline RV and LV volumes were similar. Aortic occlusion increased LV pressures and volumes and RV end-systolic pressure such that RV endsystolic elastance increased without changes in RV contraction synchrony, not affected by the pericardium. Pulmonary artery occlusion increased RV end-systolic pressure but not end-systolic volume. On the subsequent beat, RV end-diastolic pressure increased, whereas LV end-diastolic volume and diastolic compliance decreased. These effects were attenuated by opening the pericardium. Contraction synchrony across longitudinal segments was unaltered by either aortic or pulmonary artery occlusion. I conclude that the determinants of systolic and diastolic ventricular interdependence are different. Increasing RV pressures causes diastolic RV-to-LV interdependence, decreasing LV diastolic compliance and dependent on an intact pericardium. An increase in LV end-systolic pressure increases RV end-systolic elastance independent of the pericardium and has a minimal effect on RV diastolic function or contraction synchrony.

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“…However, due to the impact of afterload, it cannot re ect true myocardial contractile function, and its speci city is low[18]. Suga et al [22,23] studied invasive left ventricular pressure-volume loops and showed that regardless of the contractile state of the left ventricle, the pressure-volume area was linearly correlated with myocardial oxygen consumption.…”

Section: Discussionmentioning

confidence: 99%

Value of Left Ventricular Pressure–Strain Loops in the Quantitative Assessment of Myocardial Function in Patients with Nonobstructive Hypertrophic Cardiomyopathy

Ran

Zhang

et al. 2021

Preprint

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Purposes: The purposes of this study were to use noninvasive Left ventricular pressure-strain loops (LV-PSLs) to compare the various myocardial work indices in patients with noninvasive hypertrophic cardiomyopathy (NHCM) and to evaluate the clinical application of myocardial work to the evaluation of NHCM patients.Method: 80 NHCM patients and 45 healthy subjects were enrolled. All the selectors underwent Echocardiography examination. Dynamic images of standard apical three-chamber, four-chamber, and two-chamber view were collected, the myocardial work indices of left ventricle were measured by LV-PSLs. The difference in myocardial work indices between two groups and various myocardial work indices in different types of hypertrophic cardiomyopathy were compared.Results: There were no significant difference in the general clinical data between the NHCM group and control; myocardial work indices of HCM were lower compared with control group except global work waste (GWW); The myocardial work between all three types of NHCMs was also different, particularly in global construction work (GCW); the intra- and inter observer consistency of myocardial work indices were good.Conclusion: Myocardial work assessed by the LV-PSLs could reflect myocardial work in NHCM patients at the early stage and quantitatively assess regional and global myocardial function, providing an accurate and convenient imaging method for early detection of the subclinical status of NHCM patients.

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Pressure-volume loops: A dynamic approach to the assessment of ventricular function

Cited by 30 publications

References 77 publications

Impact of Brachial-Ankle Pulse Wave Velocity on Myocardial Work by Non-invasive Left Ventricular Pressure-Strain in Non-hypertensive and Hypertensive Patients With Preserved Left Ventricular Ejection Fraction

Impact of Brachial-Ankle Pulse Wave Velocity on Myocardial Work by Non-invasive Left Ventricular Pressure-Strain in Non-hypertensive and Hypertensive Patients With Preserved Left Ventricular Ejection Fraction

Dynamic right and left ventricular interactions in the pig

Value of Left Ventricular Pressure–Strain Loops in the Quantitative Assessment of Myocardial Function in Patients with Nonobstructive Hypertrophic Cardiomyopathy

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