2014
DOI: 10.1021/nn5025829
|View full text |Cite
|
Sign up to set email alerts
|

Pressure–Voltage Trap for DNA near a Solid-State Nanopore

Abstract: We report the formation of a tunable single DNA molecule trap near a solid-state nanopore in an electrolyte solution under conditions where an electric force and a pressure-induced viscous flow force on the molecule are nearly balanced. Trapped molecules can enter the pore multiple times before escaping the trap by passing through the pore or by diffusing away. Statistical analysis of many individually trapped molecules yields a detailed picture of the fluctuation phenomena involved, which are successfully mod… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

6
87
0

Year Published

2014
2014
2023
2023

Publication Types

Select...
8

Relationship

1
7

Authors

Journals

citations
Cited by 61 publications
(93 citation statements)
references
References 31 publications
(67 reference statements)
6
87
0
Order By: Relevance
“…The red curve is the exact MF result obtained from the numerical solution of the PB Eq. (20). One notes that the Donnan approximation Eq.…”
Section: Drift Velocity Reversalmentioning
confidence: 99%
See 1 more Smart Citation
“…The red curve is the exact MF result obtained from the numerical solution of the PB Eq. (20). One notes that the Donnan approximation Eq.…”
Section: Drift Velocity Reversalmentioning
confidence: 99%
“…Recent advancements in nanotechnology have significantly improved the reliability of the sequencing techniques. More precisely, the use of solidstate nanopores of various size and charge compositions now offers a wide range of functionalities that can allow to improve the resolution of the method [10][11][12][13][14][15][16][17][18][19][20][21][22][23]. The technological progress requires development of theoretical models that can relate the tunable system parameters to experimentally observable quantities such as polymer capture rates, translocation times, and the ionic current blockade.…”
Section: Introductionmentioning
confidence: 99%
“…Polymer confinement occurs in nanotechnology devices, such as nanopore sequencing [3,29], DNA bar coding [5], and polymer separation devices [4].…”
Section: Summary and Discussionmentioning
confidence: 99%
“…This problem has attracted interests due to its applications in the design of nanotechnology devices [3][4][5]. It also helps in obtaining more knowledge of polymers confined in biological environments [6,7].…”
Section: Introductionmentioning
confidence: 99%
“…The insulating, impermeable SiN x thus acts as a physical barrier and as a support for the channel through which ions and molecules can pass under the influence of an electric field or other suitable driving force. [21][22][23][24][25][26][27][28][29][211][212][213][214][215][216] The most common sensing configuration is the so-called resistive-pulse sensing mode (Fig. 10).…”
Section: Nanofluidic Sample Cellsmentioning
confidence: 99%