Pressure-painful scalp arteries in children and adolescents suffering from migraine

Abstract

Scalp arteries are frequently painful on pressure in children and adolescents with migraine, both in the absence of and during a migraine attack. Painful arteries suggest hypersensitivity of periarterial nociceptive afferents.

The role of the neurovascular scalp structures in migraine

“…With a stronger digital pressure (between 1.0 and 2.5 kg/cm 2 ), our group found that a large percentage of migraineurs have one or more scalp arteries painful to pressure, both during and in absence of a migraine attack (12). This is also the case in children and adolescents (13). As a control procedure we applied finger pressure alongside the arteries, which was significantly less efficacious.…”

“…the presence of pain-activating peptides. This is also present in a small percentage of healthy people (12,13). It should be noted that scalp muscles also frequently present pressure-painful points in migraine (14,15), and sometimes in healthy people (16).…”

Youth and Parent Appraisals of Participation in a Study of Spontaneous and Induced Pediatric Clinical Pain

“…There are research precedents for inducing pain in clinically ill youth for therapeutic and nontherapeutic purposes. In our literature search, and consistent with a prior literature review by Birnie et al (Birnie et al, 2014), we did not find appraisals of the acceptability of induced pain using a variety of protocols in youth with the following conditions: chronic pain in general (Evans, Tsao, & Zeltzer, 2008; Tsao, Evans, Seidman, & Zeltzer, 2012; Zeltzer et al, 2002); sickle cell disease (Gil et al, 2001; Gil et al, 1997; O’Leary, Crawford, Odame, Shorten, & McGrath, 2014); myofascial pain (Tsao et al, 2012; Zeltzer et al, 2002); fibromyalgia (Reid, McGrath, & Lang, 2005); complex regional pain syndrome (Tsao et al, 2012; Zeltzer et al, 2002); extracephalic tenderness (Metsahonkala et al, 2006); headache (tension) (Birnie et al, 2011; Ciabchett, Celeste Serci, Madeddu, Cossu, & Giuseppina Ledda, 2011; de Oliveira & Valenca, 2012; Evans et al, 2008; Fernandez-de-Las-Penas et al, 2010; Metsahonkala et al, 2006; Smith, Martin-Herz, Womack, & McMahon, 1999; Tsao et al, 2012); migraine (Ciabchett et al, 2011; de Oliveira & Valenca, 2012; Smith et al, 1999; Tsao et al, 2012; Zeltzer et al, 2002); arthritis (Gualano et al, 2010; Reid et al, 2005; Thastum, Zachariae, Scholer, Bjerring, & Herlin, 1997; Zeltzer et al, 2002); joint pain (Tsao et al, 2012); limb pain (Evans et al, 2008); back pain (Evans et al, 2008; Zeltzer et al, 2002); neck pain (Evans et al, 2008); chest pain (Zeltzer et al., 2002); neurovisceral pain (Tsao et al., 2012); recurrent and functional abdominal pain (Apley, Haslam, & Tulloh, 1971; Birnie et al, 2011; Dufton, Dunn, Slosky, & Compas, 2011; Dufton et al, 2008; Evans et al, 2008; Feuerstein, Barr, Francoeur, Houle, & Rafman, 1982; Tsao et al, 2012; Walker, Williams, Smith, Garber, Van Slyke, & Lipani, 2006; Walker, Williams, Smith, Garber, Van Slyke, Lipani, et al, 2006; Williams, Blount, & Walker, 2011; Zeltzer et al, 2002; Zohsel, Hohmeister, Flor, & Hermann, 2008); and surgical pain (Srikandarajah & Gilron, 2011). The perspectives of youth and their families concerning instigation of pain in these settings would be of inter...…”