Pressão Arterial em jovens como marcador de risco cardiovascular. Estudo do Rio de Janeiro

Abstract

Background: The study of the cardiovascular risk variables in young populations is fundamental to establish primary prevention strategies.

Blood Pressure in Adolescence, Adipokines and Inflammation in Young Adults. The Rio de Janeiro Study

“…Corroborating the literature 2,8-14,29 , the present cohort showed higher prevalence of mean insulin and insulin resistance as assessed by HOMA-IR in early adulthood in GH individuals, thus reflecting a more unfavorable metabolic profile in this population. This group also had higher serum leptin levels in comparison to GN and lower mean adiponectin than GN, although the latter without a statistically significant difference.…”

“…In the Muscatine study 23 , the authors demonstrated that more than half of the hypertensive children were also obese. In our country, several publications, especially those of the RJS cohort, had already suggested the importance of body composition in the determinism of BP in children and adolescents 8-14,24,25 .…”

“…Two classic international studies, the Bogalusa Heart Study 26 and the CARDIA study 27 , reinforced the knowledge that central obesity as verified by an abnormal AC represents an important marker of coronary atherosclerosis in young populations. In Brazil, studies analyzing the relationship between AC and other RF, such as HBP 14,22 , have shown conflicting results, thus suggesting the need to improve the knowledge on the AC cut-off points in our population, as well as its relations to other RF and the determinism of further CVD. In the present study, a higher prevalence of increased AC was observed at A2 in hypertensive individuals (GH) in adolescence.…”

“…This study population is from the Rio de Janeiro Study (RJS) 8-14 , and is part of a line of research on BP and other cardiovascular RF in young individuals and their families, that has been developed in the University of the State of Rio de Janeiro since 1983. It was divided into two stages: in the first stage, children between 6 and 9 years of age, n = 3109 (1983-1986) were evaluated; in the second stage, adolescents between 10 and 15 years of age, n = 3906 (1987 - 1989), called target-students, were evaluated, and normality curves of systolic (SBP) and diastolic blood pressure (DBP) were obtained for each gender and age.…”

Velocidade da onda de pulso, pressão arterial e adipocitocinas em adultos jovens: estudo do Rio de Janeiro

“…The present study is part of the Rio de Janeiro study (ERJ) [13][14][15] , a longitudinal line of research on blood pressure (BP) and other cardiovascular RF in children and adolescents and their families, which has been developed since 1983 and aims to evaluate the association between PWV and BP, anthropometric and metabolic variables, including adipocytokines, in young adults.…”