“…MAP-MRI metrics have been shown to be sensitive to microstructural changes in brain tissues in various neurological conditions and neurodevelopment (Bouhrara et al, 2022;C.-L. Chen, Shih, et al, 2019;H.-J. Chen et al, 2021;Le et al, 2020;Ma et al, 2020;Moody et al, 2022;Mustafi et al, 2019;Pines et al, 2020;Qiu et al, 2022;Sun et al, 2022;Wang, He, et al, 2022;Wang, Deng, et al, 2022;Xie et al, 2022), with one study documenting an association between RTOP and clinical measures in mTBI patients assessed within 15 days of injury (Y.-C. Wu et al, 2018). To our knowledge, however, no prior work has applied the MAP-MRI technique to investigate the longterm effects of concussion.…”