Preserved egg white alleviates DSS-induced colitis in mice through the reduction of oxidative stress, modulation of infl ammatory cytokines, NF-κB, MAPK and gut microbiota composition

The maca protein ameliorates DSS-induced colitis in mice by modulating the gut microbiota and production of SCFAs

“…The dominant bacteria in groups MPD and DMP after MCP intervention were mainly Muribaculceae and norank_f_muribaculceae , which were the same as those in group N, followed by Lactobacillus , Oscillospira , Akkermansia and Bifidobacterium , all of which have been reported to be probiotics that help prevent IBD. 9,16,41 These results indicate that MCP treatment could make the composition of dominant microorganisms close to those of the healthy group, and early intervention with MCP could promote the abundance of beneficial bacteria and inhibit the growth of potentially harmful microorganisms in the gut. The role of MCP in IBD is realized through the regulation of gut microbiota, especially some specific microbiome.…”

“…Li et al and Sun et al both reported that in a DSS-induced colitis mouse model, intervention with proteins from different dietary sources can reduce the abundance of Lachnospiraceae and increase the abundance of Muribaculaceae . 16,41…”

“…In DSS-induced colitis in mice, the preserved egg-white intervention increases the relative abundance of beneficial bacteria such as Lachnospiraceae , Muribaculaceae , and Ruminococcaceae , as well as decreases that of harmful bacteria such as Proteobacteria . 41 Therefore, MCP may alleviate DSS-induced colitis by increasing the relative abundance of nnorank_f_ Muribaculaceae , Lactobacillus , Oscillospira , Akkermansia and Bifidobacterium , as well as reducing the abundance of Lachnospiraceae_NK4A136_group , Bacteroides , Desulfovibrio , Prevotella , Helicobacter and Sutterella .…”

“…In addition, compared with the N group, the abundance of Lactobacillaceae and Bifidobacteriaceae in the MP group was significantly increased ( p < 0.05), indicating that MCP itself could change the composition of gut microbiota and increase the generation of beneficial bacteria. Li et al and Sun et al both reported that in a DSS-induced colitis mouse model, intervention with proteins from different dietary sources can reduce the abundance of Lachnospiraceae and increase the abundance of Muribaculaceae 16,41.…”

The process of hypertension induced by high-salt diet: Association with interactions between intestinal mucosal microbiota, and chronic low-grade inflammation, end-organ damage

“…The level of inflammatory biomarkers (high-sensitive C-reactive protein and various cytokines) were increased in patients with hypertension and the production of these biomarkers involves different cells, for example, interleukin-1β (IL-1β) is produced by myeloid cells, and interleukin-1α (IL-1α) is released by epithelial cells and endothelial cells (Xiao and Harrison, 2020). Pro-inflammatory T cell aggravate hypertension by releasing pro-inflammatory cytokines, such as interleukin-17A (IL-17A) and TNF-α (Li et al, 2023). With the development of microbiology and many scientific technologies, the complex interaction of food, microorganisms and their metabolites with the intestinal cavity and intestinal mucosa and the immune system has been revealed (Clemente et al, 2018).…”