Preservación con Celsior en trasplante renal: Nuestra experiencia

Sanz, Pedro J.; Revilla, F.J. Burgos; Letosa, R. Marcén; Santos, Julio Pascual; Rivas, J.L. Merino; Mirete, J. Ortuño

doi:10.4321/s0210-48062004000100009

Actas Urol Esp

2004

DOI: 10.4321/s0210-48062004000100009

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Preservación con Celsior en trasplante renal: Nuestra experiencia

Pedro J. Sanz

F.J. Burgos Revilla

R. Marcén Letosa

et al.

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2019

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“…A multicenter randomized study of 187 renal transplants showed that the kidney preservation by Celsior solution was equivalent to that of UW solution in DGF rate (31.3% vs. 33.9%) and 2-year graft survival (84% vs. 75%) 46 . The incidence of acute tubular necrosis was much lower in the Celsior group than in the UW group (23% vs. 36%) after transplantation 47 . These results indicated equivalence, and even some advantages, of Celsior solution when compared with the traditional UW solution.…”

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confidence: 76%

Preservation Solutions for Kidney Transplantation: History, Advances and Mechanisms

et al. 2019

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Solid organ transplantation was one of the greatest medical advances during the past few decades. Organ preservation solutions have been applied to diminish ischemic/hypoxic injury during cold storage and improve graft survival. In this article, we provide a general review of the history and advances of preservation solutions for kidney transplantation. Key components of commonly used solutions are listed, and effective supplementations for current available preservation solutions are discussed. At cellular and molecular levels, further insights were provided into the pathophysiological mechanisms of effective ingredients against ischemic/hypoxic renal injury during cold storage. We pay special attention to the cellular and molecular events during transplantation, including ATP depletion, acidosis, mitochondrial dysfunction, oxidative stress, inflammation, and other intracellular mechanisms.

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Preservation Solutions for Kidney Transplantation: History, Advances and Mechanisms

et al. 2019

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Preservación con Celsior en trasplante renal: Nuestra experiencia

Cited by 1 publication

References 2 publications

Preservation Solutions for Kidney Transplantation: History, Advances and Mechanisms

Preservation Solutions for Kidney Transplantation: History, Advances and Mechanisms

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