Presepsin Levels in Infection-Free Subjects with Diabetes Mellitus: An Exploratory Study
Dimitrios Kouroupis,
Ioanna Zografou,
Aikaterini Balaska
et al.
Abstract:Systemic inflammation has been recognized as the cause and consequence of metabolic dysregulation in diabetes mellitus (DM). Presepsin has recently emerged as a promising biomarker for the detection of bacterial infections and sepsis. There is evidence that gut dysbiosis results in the increased circulating concentrations of Gram-negative bacteria lipopolysaccharide, the linkage of presepsin, which in turn promotes insulin resistance and correlates with the risk of diabetic complications. Thus, we hypothesized… Show more
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