Presentation, treatment, and outcome of oral cavity cancer: A national cancer data base report

Abstract

This study addressed many issues related to oral cancer that have been previously discussed in the literature. The demographic, site, stage, histologic, and survival data available for this large number of cases in the NCDB allowed an accurate characterization of the contemporary status of oral cancer in the United States.

Demographic Risk Factors, Affected Anatomical Sites and Clinicopathological Profile for Oral Squamous Cell Carcinoma in a North Indian Population

“…Around more than 300,000 patients are annually estimated have to oral cancer worldwide (Funk et al, 2002;Rautava et al, 2007). However, OSCC shows a geographical variation with respect to the age, site, sex and habits of the population (Mehrotra et al, 2008).…”

Conditional survival in head and neck squamous cell carcinoma

“…SEER descriptions of chemotherapeutic and radiation therapy techniques are somewhat inexact, and do not differentiate by chemotherapy regimen or radiotherapy fields implemented. As treatments evolve over time, CS calculations using the methodology described overweight those patients with greater follow-up, necessarily reducing the impact of newer treatment methods reflected in other large composite datasets, 25,[27][28][29] as well as possible shifts in the etiology of HNSCC. 30 Additionally, several categorical variables within the subsite designation are poorly formulated (ie, ''Other Oral Cavity and Pharynx'') and provide potential for inaccurate coding of similar tumors.…”

Enhanced Interferon Signaling Pathway in Oral Cancer Revealed by Quantitative Proteome Analysis of Microdissected Specimens Using 16O/18O Labeling and Integrated Two-dimensional LC-ESI-MALDI Tandem MS

“…Over the past 2 decades, the overall incidence and morbidity rates of patients with oral cancer have increased continuously. Epidemiological studies show that ϳ50 -70% of patients who undergo surgery for oral cancer die within 5 years (1)(2)(3)(4)(5)(6). This poor prognosis predominantly reflects late stage presentation, secondary cancer occurrence, local recurrence, and metastasis (7) as well as the lack of suitable markers for cancer detection.…”