Presentation of idiopathic retroperitoneal fibrosis in the pediatric population

Miller, O. Fred; Smith, Loren J.; Ferrara, Elizabeth; McAleer, Irene M.; Kaplan, George W.

doi:10.1016/s0022-3468(03)00590-6

Cited by 44 publications

(17 citation statements)

References 23 publications

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“…There was no substantial difference in the incidence of advanced atherosclerosis between patients with chronic periaortitis and healthy controls (Uibu et al, 2004;Breems et al, 2000). Also, chronic periaortitis may affect patients without atherosclerosis, and it has been reported in pediatric patients (Miller et al, 2003). A recent study showed no significant differences in anti-ox-LDL antibody levels between patients with chronic periaortitis and controls (van Bommel et al, 2011).…”

Section: Pathogenesismentioning

confidence: 88%

“…On the other hand, data regarding the incidence of the aneurysmal forms of chronic periaortitis in the whole population are lacking, however they represent about 4% to 10% of all abdominal aortic aneurysms von Fritschen et al, 1999;Yusuf et al, 2007). Chronic periaortitis frequently develops in middle-aged adults with a mean age of approximately 60 years, but it may also occur in children (Miller et al 2003;Uibu et al, 2004;. Men are affected two to three times as often as women and that is even more pronounced in the inflammatory abdominal aortic aneurysms (Gilkeson & Allen 1996;Uibu et al, 2004;.…”

Section: Epidemiologymentioning

confidence: 99%

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Chronic Periaortitis as a Systemic Autoimmune Disease

Suh¹

2011

Autoimmune Disorders - Pathogenetic Aspects

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Section: Pathogenesismentioning

confidence: 88%

Section: Epidemiologymentioning

confidence: 99%

Chronic Periaortitis as a Systemic Autoimmune Disease

Suh¹

2011

Autoimmune Disorders - Pathogenetic Aspects

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“…It is of unknown etiology, with very few pediatric cases described. Due to its unspecific presentation, diagnosis is often delayed, and its biological behavior can be unpredictable [24,25].…”

Section: Discussionmentioning

confidence: 99%

Abdominal inflammatory masses mimicking neoplasia in children—experience of two centers

et al. 2005

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Despite progress in modern imaging, some inflammatory masses are difficult to distinguish clinically from neoplastic processes. In such cases the pathology report has a great distinctive value, but even then the final diagnosis may be difficult to reach. Eight patients with abdominal tumors of inflammatory origin were treated in two institutions, the Department of Pediatric Surgery of the Medical University of Gdansk, Poland, and Helios Center of Pediatric Surgery in Berlin, Germany, during the last 10 years. Four tumors were located in the pelvis, two in the liver, and two in the colonic mesentery. Five of them were inflammatory pseudotumors (two subclassified as inflammatory fibrosarcoma), one had nonspecific inflammatory changes, one was diagnosed as idiopathic retroperitoneal fibrosis, and one was diagnosed as bacillary angiomatosis. All patients underwent surgical tumor biopsy, excisional in four and incisional in four. All but two children underwent macroscopically complete tumor excision (four primarily, two secondarily). In one case the tumor resolved with antibiotherapy. Surgery in retroperitoneal masses was often extensive and associated with significant complications because of invasive tumor growth. In conclusion, intraabdominal inflammatory lesions may closely mimic neoplasia in children. Clinical doubts result in repeated biopsies, and for this reason excisional biopsy should be preferred. In some cases, when excisional biopsy is not feasible due to invasive growth of the tumor, delayed complete mass excision should follow, despite occasional significant morbidity. The etiology and exact nature of inflammatory pseudotumors are still obscure, and it is unknown whether they represent inflammatory lesions or true neoplasia.

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“…[13] Children having the disease are also reported-23 cases in the English-language literature by 2003. [14] Atherosclerosis was considered to be the reason of the predominance of male sex. Genetic transition was reported, with cases diagnosed in twins and siblings.…”

Section: Case Twomentioning

confidence: 99%