Present Status of Polysaccharide Vaccines in the Prevention of Meningococcal Disease

Gold, Ronald; Ml, Lepow

doi:10.1016/s0065-3101(22)00718-6

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1979

1989

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Cited by 18 publications

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Penicillin-Insensitive Pneumococci

Ahronheim¹

1979

Am J Dis Child

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I. Marks, MD, FRCP(C) \s=b\Infections due to pneumococci with decreased susceptibility (or resistance) to penicillin have been infrequently recognized. Our experience and that of others suggest that (1) penicillin susceptibility testing of significant pneumococcal isolates should become routine; (2) penicillin may not be adequate therapy for CNS infections due to pneumococci whose penicillin minimal inhibitory concentration is > 0.1 \g=m\g/ml; and (3) long-term penicillin "prophylaxis" may be inappropriate in the splenectomized patient in areas where these organisms are prevalent.

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