Present and future perspectives of virtual chromoendoscopy with <scp>i</scp>‐scan and optical enhancement technology

Neumann, Helmut; Fujishiro, Mitsuhiro; Wilcox, C. Mel; Mönkemüller, Klaus

doi:10.1111/den.12190

Cited by 53 publications

(56 citation statements)

References 35 publications

(65 reference statements)

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“…Recently i-scan OE was evaluated for assessment of inflammatory changes in ulcerative colitis. 16,17 The diagnostic accuracy of i-scan OE was calculated against histology using two specific histological scoring systems. Overall, i-scan OE showed a significant correlation with histology.…”

Section: Optical Chromoendoscopy In Ibdmentioning

confidence: 99%

Advanced endoscopic imaging for diagnosis of inflammatory bowel diseases: Present and future perspectives

Sivanathan

Tontini

Möhler

et al. 2018

Digestive Endoscopy

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Crohn's disease and ulcerative colitis are chronic inflammatory bowel diseases (IBD) causing severe damage of the luminal gastrointestinal tract. Differential diagnosis between both disease entities is sometimes awkward requiring a multifactorial pathway, including clinical and laboratory data, radiological findings, histopathology and endoscopy. Apart from disease diagnosis, endoscopy in IBD plays a major role in prediction of disease severity and extent (i.e. mucosal healing) for tailored patient management and for screening of colitis-associated cancer and its precursor lesions. In this state-of-the-art review, we focus on current applications of endoscopy for diagnosis and surveillance of IBD. Moreover, we will discuss the latest guidelines on surveillance and provide an overview of the most recent developments in the field of endoscopic imaging and IBD.

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Section: Optical Chromoendoscopy In Ibdmentioning

confidence: 99%

Advanced endoscopic imaging for diagnosis of inflammatory bowel diseases: Present and future perspectives

Sivanathan

Tontini

Möhler

et al. 2018

Digestive Endoscopy

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“…The data from five case-control studies and two cohort studies in Japan demonstrated that photofluoroscopy for gastric cancer screening can decrease gastric cancer mortality by 40-60% [12]. By now, many new advanced approaches providing better visualization of gastric mucosa lesions have been developed, such as chromoendoscopy [62], confocal laser endomicroscopy [63], narrow-band imaging endoscopy [64], magnifying endoscopy [65] and narrow-band imaging with magnifying endoscopy [66]. A large number of studies showed that these new advanced endoscopic imaging technologies have better accuracy for diagnosing premalignant gastric lesions than standard ‘white light' endoscopy [67,68,69].…”

Section: Prevention Strategies For Gastric Cancermentioning

confidence: 99%

Etiology and Prevention of Gastric Cancer

Cheng

Lin

2016

Gastrointest Tumors

129

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Background: Gastric cancer is a heterogeneous malignant disease associated with environmental and genetic predisposing factors. While gastric cancer incidence and mortality fell greatly globally over the past decades, it remains the fourth cause of cancer-related death worldwide. Thus, prevention of gastric cancer is still a major strategy for improvement of gastric cancer prognosis. Summary:Helicobacter pylori infection has been demonstrated to be a major risk factor for the development of gastric cancer. Unhealthy diet and lifestyle, including high-salt food, smoking and drinking, are able to induce genotypic and phenotypic transformation of gastric epithelial cells. Gene mutations (such as E-cadherin) in stomach epithelial cells are major genetic causes for gastric cancer. The eradication of H. pylori has been demonstrated to be an effective approach for primary prevention of gastric cancer. Increased intake of a diet rich in vegetables and fresh fruits as well as smoking cessation have been shown to reduce the incidence of gastric cancer. The secondary prevention strategy is to screen premalignant gastric lesions by endoscopy. Biomarker tests are also reliable methods to identify gastric precancerous lesions. Endoscopy screening is still the gold standard for diagnosis of gastric cancer. Key Message:H. pylori infection, a diet rich in salted and/or smoked food and red meat, as well as gene mutations are major risk factors for the development of gastric cancer. Practical Implications: The eradication of H. pylori is a major primary preventive strategy of gastric cancer. A healthy lifestyle, including increased intake of a diet rich in fruit and vegetables, reduced intake of salted and smoked food and red meat, a reduction of alcohol intake as well as smoking cessation will be effective approaches for the prevention of gastric cancer.

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“…I-SCAN improves polyp characterization and visualizes the architectural subtleties in the mucosa [30][31][32][33] (Figures 3, 4). …”

Section: I-scanmentioning

confidence: 99%

Advanced Endoscopic Imaging Techniques for the Study of Colonic Mucosa in Patients with Inflammatory Bowel Disease

Ştefănescu

Pereira

Filip

et al. 2016

Romanian Journal of Internal Medicine

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Background. Crohn's disease and ulcerative colitis are inflammatory bowel diseases (IBD) associated with colorectal cancer risk in long-standing diseases. In order to assess the colonic mucosa and to discover dysplastic or neoplastic lesions, advanced endoscopic techniques are needed. Such techniques are detailed in this review: chromoendoscopy, autofluorescence imaging (AFI), narrow band imaging (NBI), i-SCAN, Fujinon Intelligent Color Enhancement (FICE) and confocal laser endomicroscopy (CLE).Aim. The aim of the review is to describe and establish the clinical impact of advanced endoscopic techniques, that could be used in IBD patients'examination in order to assess mucosal healing, microscopic inflammation, dysplasia or neoplasia.Materials and Methods. A literature research about new endoscopic approaches of patients with IBD was made. Results.A lot of studies have been performed to reveal which imaging technique might be used for IBD surveillance. Regarding dysplasia or neoplasia detection and mucosal healing or inflammation assessment, CE proved to be superior to white light endoscopy (WLE), while NBI and AFI did not show an encouraging result. I-SCAN did not improve the colonoscopy quality while FICE has been used in a few studies. CLE could be used to characterize a lesion, providing the same results as conventional histology.Conclusion. At the moment, CE is the only technique which has been included in guidelines for IBD surveillance. CLE can be used to assess any lesion detected with WLE during surveillance, while the other imaging techniques require more studies to determine their efficacy or inefficacy.

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Present and future perspectives of virtual chromoendoscopy with i‐scan and optical enhancement technology

Cited by 53 publications

References 35 publications

Advanced endoscopic imaging for diagnosis of inflammatory bowel diseases: Present and future perspectives

Advanced endoscopic imaging for diagnosis of inflammatory bowel diseases: Present and future perspectives

Etiology and Prevention of Gastric Cancer

Advanced Endoscopic Imaging Techniques for the Study of Colonic Mucosa in Patients with Inflammatory Bowel Disease

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