Presence of serum creatine kinase isoenzymes in liver failure with cerebral involvement

Lemberg, A; Werber, D.H.; Gilardoni, Adrián; Magrino, H.J.

doi:10.1016/0009-8981(77)90048-1

Cited by 10 publications

(2 citation statements)

References 11 publications

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“…There have been only few data so far on the occurrence of CK-BB isoenzyme in serum of healthy adults and patients suffering from dif ferent diseases (3)(4)(5)(6)(7)(8)(9)12). In the past it was assumed that no CK-BB in human could be detected (4,13).…”

Section: Discussionmentioning

confidence: 99%

Creatine Kinase Isoenzyme BB in Serum of Patients undergoing Chronic Hemodialysis and with Kidney Transplant

Jung¹,

Scholz²,

Precht³

1979

Enzyme

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The activity of creatine kinase isoenzyme BB (CK-BB) was determined in serum of healthy adults and in patients undergoing maintenance hemodialysis and with kidney transplant. In the healthy adults examined, an activity of 0.56 ± 0.16 U/l (x ± SD) was found. The arithmetic mean of CK-BB activity in patients with renal insufficiency under hemodialysis was 1.42 ± 0.87 U/l and differed from that of the healthy group. The CK-BB activity in patients with kidney transplant was not different from that of the control group. The occurrence of CK-BB in serum is discussed from diagnostic and methodological point of view.

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Section: Discussionmentioning

confidence: 99%

Creatine Kinase Isoenzyme BB in Serum of Patients undergoing Chronic Hemodialysis and with Kidney Transplant

Jung¹,

Scholz²,

Precht³

1979

Enzyme

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“…'Από τούς'Α. Lemberg καί συν 45. αναφέρθηκε ή παρουσία τοϋ ίσοενζύ μου ΒΒ τής CPK στον ορό ασθενών οί όποιοι εμφάνιζαν οξεία έγκεφαλοπάθεια καί κώμα, λόγω ηπατικής ανεπάρκειας οφειλόμενης σέ οξεία ίογενή ηπατίτιδα ή σέ χρονία ηπατική πάθηση.…”

unclassified

Μεταβολες Σε Συναρτηση Με Τον Χρονο Των Ισοενζυμων Της CPK Και Της LDH Σε Οξειες Ενδοκοιλιακες Καταστασεις. (Πειραματικη Μελετη)

Σακελλαριου¹

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Serum creatine kinase isoenzymes behavior in hepatic failure with encephalopathy

et al. 1981

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Serum creatine kinase isoenzymes were determined in 24 patients with hepatic failure. Hepatic failure was due to severe acute and chronic liver disease. The 24 patients presented different degrees of coma. Nineteen cases (seven hepatitis and 12 cirrhosis) in coma grades III and IV showed the presence in serum of BB, brain and MB, myocardial isoenzymes. Follow up in six of these cases demonstrated that worsening or improvement was accompanied by an increase or decrease of this brain isoenzyme concentration. The leakage from their respective tissues of the brain and myocardial creatine kinase isoenzymes is probably due to the toxic and surface activity properties of serum free fatty acids, bile salts, and bilirrubin, which increase, among other factors, in these pathological entities.

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Presence of serum creatine kinase isoenzymes in liver failure with cerebral involvement

Cited by 10 publications

References 11 publications

Creatine Kinase Isoenzyme BB in Serum of Patients undergoing Chronic Hemodialysis and with Kidney Transplant

Creatine Kinase Isoenzyme BB in Serum of Patients undergoing Chronic Hemodialysis and with Kidney Transplant

Μεταβολες Σε Συναρτηση Με Τον Χρονο Των Ισοενζυμων Της CPK Και Της LDH Σε Οξειες Ενδοκοιλιακες Καταστασεις. (Πειραματικη Μελετη)

Serum creatine kinase isoenzymes behavior in hepatic failure with encephalopathy

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