Presence of Kaposi's Sarcoma and of Behcet’s Disease Concomitantly in a Patient

Abstract

Iatrogenic Kaposi’s sarcoma is a subtype of Kaposi’s sarcoma (KS), which is a vascular malignant tumor and is seen in organ transplant recipients and in patients receiving immunosuppressive therapy due to other reasons. We describe a case of Behcet's disease associated with Kaposi's sarcoma occurring simultaneously in a 50-year-old male patient. Colchicine and steroids were administered for his mucocutaneous findings and polyarthritis. In few months on therapy, four symmetric, brown- red coloured, asymptomatic macules developed on the inner surface of his left foot. In histopathologic specimens; CD34 positive, atypical spindle cells with swollen nuclei formed bundles and vascular spaces filled with erythrocytes. The patient was diagnosed as KS clinically and histopathologically. HHV-8 DNA was positive with PCR. Regression was observed in the lesions after the cessation of corticosteroid treatment.