Presence of hemagglutination inhibition and neutralization antibodies to Japanese encephalitis virus in wild pigs on an offshore island in Singapore

See, E’Ein; Tan, Hwee Cheng; Wang, Dongling; Ooi, Eng Eong; Lee, May-Ann

doi:10.1016/s0001-706x(01)00212-1

Cited by 28 publications

(19 citation statements)

References 6 publications

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“…JEV was first isolated in 1935 in Tokyo, Japan, from the human brain of a fatal Japanese encephalitis (JE) case. JEV is transmitted by Culex mosquitoes in an epizoonotic cycle [1][2][3], and is a serious cause of human morbidity and mortality in Asia.…”

Section: Discussionmentioning

confidence: 99%

Detection of antibodies to Japanese encephalitis virus in the wild boars in Hiroshima prefecture, Japan

et al. 2007

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Serum specimens were collected from 25 wild boars in Hiroshima prefecture located in the western region of Japan from November 2004 to February 2005. The sera were tested for antibodies to Japanese encephalitis virus (JEV) by IgM capture and IgG enzyme-linked immunosorbent assays (ELISA), and plaque reduction neutralization test. Seventeen samples (68%) were positive for neutralizing antibody to JEV. All the neutralizing antibody-positive samples were positive for IgG-ELISA. One was also positive for IgM. The results indicate that approximately 70% of the wild boars were positive for anti-JEV antibody, and raises the possibility that wild boars may play a role in the infectious cycle of JEV in this region.

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Section: Discussionmentioning

confidence: 99%

Detection of antibodies to Japanese encephalitis virus in the wild boars in Hiroshima prefecture, Japan

et al. 2007

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“…This is most likely due to exposure in early childhood as JE was more prevalent in the 1980s [25]. However, the risk for JE in Singapore has not been totally eliminated, as JE virus was still detected in pigs on Singapore's offshore islands [26]. Serological cross-reactivity exists between dengue and JE virus and this needs to be taken into account when performing assays for dengue antibody prevalence [27][28][29].…”

Section: Discussionmentioning

confidence: 99%

Serological evidence for the co-circulation of multiple dengue virus serotypes in Singapore

et al. 2005

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We did a seroepidemiological study to determine the circulating dengue virus serotypes and the extent to which the Singapore population has been exposed to multiple dengue virus serotypes, using the plaque reduction neutralization assay (PRNT). Of 164 enrolled subjects aged between 18-30 years, 49 subjects (29.8%) were PRNT positive for at least one dengue serotype. The seroprevalence was 39 (23.8%) for dengue virus serotype 1, 37 (22.6%) for type 2, 43 (26.2%) for type 3, and 30 (18.3%) for type 4. Of the 49 subjects with PRNT-positive dengue virus results, 28 (57.1%) were positive to all four virus serotypes, seven (14.3%) to three serotypes, two (4%) to two serotypes, and 12 (24.5%) to a single serotype. All four dengue virus serotypes circulate in Singapore, and a substantial proportion of the adult population in Singapore had exposure to more than one dengue virus serotype. In spite of multiple circulating types, the rate of dengue haemorrhagic fever is low in Singapore.

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“…A study was conducted to determine the presence of prevalence with hemagglutination inhibition (HI) and neutralization antibodies against JEV in wild pigs of an island in Singapore showing positive results for antibodies against JEV (See et al, 2002).…”

Section: Singaporementioning

confidence: 99%

Japanese Encephalitis: An Emerging and Spreading Arbovirosis

Saxena¹,

Tiwari²,

Saxena³

et al. 2011

Flavivirus Encephalitis

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Presence of hemagglutination inhibition and neutralization antibodies to Japanese encephalitis virus in wild pigs on an offshore island in Singapore

Cited by 28 publications

References 6 publications

Detection of antibodies to Japanese encephalitis virus in the wild boars in Hiroshima prefecture, Japan

Detection of antibodies to Japanese encephalitis virus in the wild boars in Hiroshima prefecture, Japan

Serological evidence for the co-circulation of multiple dengue virus serotypes in Singapore

Japanese Encephalitis: An Emerging and Spreading Arbovirosis

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