“…Reports of a trophic effect of GI-21 on rat intestinal cells in vitro (Watanabe, Matsuyama, Namba, Miyagawa, Itoh, Komatsu, Kono & Tarui, 1988 b) and in vivo (Watanabe et al 1988a) has led to the suggestion that the N-terminal amino acid sequence plays an important role in the control of intestinal growth. G -21-like immunoreactivity is widely distributed throughout the small intestine and colon, and closely follows the distribution of glucagon-like immunoreactivity (Itoh, Namba, Watanabe, Ohara, Matsuyama, Komatsu, Shinomura, Kono & Tarui, 1989).…”