“…Moreover, the present study, together with a previous one, suggests that only medical therapy results in survival of only one-third of the cases after long-term follow-up. 1,4 Consequently, a real alternative to the step-by-step strategy is the so-called Early Interventional Treatment strategy, proposing that intervention, in the presence of any sign of portal hypertension, could improve outcome. 5 In fact, following the latter strategy, excellent survival was reported both in East and West.…”