Présence et devenir des médicaments dans les eaux usées urbaines, une analyse bibliographique

Alighardashi, Abolghasem; Pons, Marie‐Noëlle; Potier, Olivier

doi:10.7202/019164ar

Cited by 4 publications

(2 citation statements)

References 103 publications

(60 reference statements)

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“…One possible explanation could be that contact points with human installations are not be the only places where MRSA transmission occur. For example, wastewater might transport antibiotics and the bacteria over hundreds of meters from the place of use [ 13 , 67 ] or contaminated bats could have contacts with micromammals inside the forest. This latter explanation seems unlikely in our case because we did not observe any MRSA strains infecting both rodents and bats.…”

Section: Discussionmentioning

confidence: 99%

Staphylococcus aureus Host Spectrum Correlates with Methicillin Resistance in a Multi-Species Ecosystem

et al. 2023

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Although antibiotic resistance is a major issue for both human and animal health, very few studies have investigated the role of the bacterial host spectrum in its dissemination within natural ecosystems. Here, we assessed the prevalence of methicillin resistance among Staphylococcus aureus (MRSA) isolates from humans, non-human primates (NHPs), micromammals and bats in a primatology center located in southeast Gabon, and evaluated the plausibility of four main predictions regarding the acquisition of antibiotic resistance in this ecosystem. MRSA strain prevalence was much higher in exposed species (i.e., humans and NHPs which receive antibiotic treatment) than in unexposed species (micromammals and bats), and in NHP species living in enclosures than those in captivity—supporting the assumption that antibiotic pressure is a risk factor in the acquisition of MRSA that is reinforced by the irregularity of drug treatment. In the two unexposed groups of species, resistance prevalence was high in the generalist strains that infect humans or NHPs, supporting the hypothesis that MRSA strains diffuse to wild species through interspecific transmission of a generalist strain. Strikingly, the generalist strains that were not found in humans showed a higher proportion of MRSA strains than specialist strains, suggesting that generalist strains present a greater potential for the acquisition of antibiotic resistance than specialist strains. The host spectrum is thus a major component of the issue of antibiotic resistance in ecosystems where humans apply strong antibiotic pressure.

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Section: Discussionmentioning

confidence: 99%

Staphylococcus aureus Host Spectrum Correlates with Methicillin Resistance in a Multi-Species Ecosystem

et al. 2023

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“…Over the last two decades, a large variety of pharmaceutical drugs including analgesics, anti-inflammatory, beta-blockers, antimicrobials, blood lipid regulators and so on, has been detected at low contents of micrograms per liter in soils, surface waters, ground waters and even in drinking waters [1][2][3][4][5][6][7][8][9]. Pharmaceutical drugs can reach aquatic environment from domestic waste or industrial wastewater, hospitals and health centers [10].…”

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confidence: 99%