Presence and Duration of Symptoms in Febrile Infants With and Without SARS-CoV-2 Infection

McLaren, Son H.; Dayan, Peter; Zachariah, Philip; McCann, Teresa A.; Lubell, Tamar R.

doi:10.1097/inf.0000000000002858

Cited by 7 publications

(4 citation statements)

References 6 publications

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“…All patients had favourable outcomes, and the incidence of complications was very low. The evidence to date has shown a higher rate of hospital admission in infants, especially in the presence of risk factors, 34 , 35 which was also the case in our study.…”

Section: Discussionsupporting

confidence: 88%

COVID-19 clinical features in primary care: COVIDPAP study

Carballal-Mariño¹,

Balaguer-Martínez²,

Vera

et al. 2022

Anales de Pediatría (English Edition)

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Section: Discussionsupporting

confidence: 88%

COVID-19 clinical features in primary care: COVIDPAP study

Carballal-Mariño¹,

Balaguer-Martínez²,

Vera

et al. 2022

Anales de Pediatría (English Edition)

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“…A fever and cough appear to be the most common symptoms in the pediatric population but are not universally present. 11,[14][15][16][18][19][20][21][22] The cough associated in children with COVID-19 generally seems to be dry, although in moderate cases, a productive cough sometimes follows. 23 Some recent case studies have reported the presence of a croup-like cough in children with COVID-19 that does not appear to be attributable to coinfection with parainfluenza virus or other common respiratory viruses.…”

Section: Discussionmentioning

confidence: 99%

A Term Infant Presenting with COVID-19 Disease at Birth and a Croup-Like Cough

et al. 2022

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Introduction: Since the original coronavirus disease 2019 (COVID-19) global outbreak, there have been increasing reports of children developing a croup-like cough associated with concurrent COVID-19 infection. Currently, there is not much information available regarding newborn infants and COVID-19 infection and the incidence of vertical transmission is thought to be rare. This novel case report depicts a term newborn infected at the time of birth with COVID-19 and includes details about the course of their complicated hospitalization. Case Report: A term infant, found to be infected at birth with COVID-19, developed respiratory distress resulting in transfer to our neonatal intensive care unit. Due to the increasing respiratory support requirements, endotracheal intubation was required on day of life (DOL) seven. Later when the infant was extubated, on DOL 21, a croup-like cough developed. Despite respiratory treatment with albuterol, budesonide, racemic epinephrine, lidocaine, pulmozyme, and a ten day course of dexamethasone, the cough persisted. A prolonged hospitalization was required and eventually the infant was discharged home on 0.4 liters per minute of oxygen via nasal cannula on DOL 95. Conclusion: As the COVID-19 virus mutates over time, there are some seemingly different presentations in both the pediatric and adult populations. The hypervigilance and sharing of new findings among providers is paramount in the treatment of infants with COVID-19 disease.

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“…Дуже рідко захворювання прогресує у вигляді інфекції нижніх дихальних шляхів [2]. У розрізі порівняння коронавірусної хвороби COVID-19 з іншим респіраторними інфекціями спостерігається подібність симптомів та загальної тривалості захворювання, з більшою тривалістю кашлю та закладеності носа серед немовлят [3].…”

Section: вступunclassified

Clinical and Epidemiological Peculiarities if Covid-19 Infection in Infants

Иванова¹,

Haras²,

Романчук³

et al. 2021

Clin. and experim. pathol.

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The aim of the research - to analyze the epidemiological and clinical peculiarities ofcoronavirus disease COVID-19 in infants compared to the older age group.Materials and methods. 188 inpatient cards of children who were hospitalized in theinfectious diseases departments of Chernivtsi Regional Children's Clinical Hospitalwith COVID-19 infection were analyzed, in particular, 63 children under 1 year of age(1st group) and 125 children aged 1 year and older (2nd group, comparison group).A complex of anamnestic, epidemiological and clinical characteristics of COVID-19infection was determined in hospitalized children.Results. During the analysis of the data it was found that the epidemiologicalsignificance was related to family contacts, unidentified non-family sources of infectionwere observed in a quarter of infants (25,4%) and 39,2% of children of group II (p<0,05). The most common clinical symptoms in the general cohort were fever, weaknessand lethargy, loss of appetite, and signs of catarrhal pharyngitis. Symptoms of upperrespiratory tract disease prevailed in infancy, in particular, most had nasal congestion(55,6% vs. 40,2%, p>0,05), 30,2% infants had rhinorrhea (16,8% in the 2nd group,p<0,05), while in the comparison group the symptoms from the lower respiratory tractdominated, in particular, cough was significant more often observed (59,2% vs. 26,9%in the 1st group, p<0,05). Lesions of the lower respiratory tract with the development ofpneumonia were significant more common in 32,0% of children in 2nd group and only in8,0% of infants (p<0,05).Conclusions. Epidemiologically, the start of COVID-19 pandemic in Chernivtsi regionwith restrictive quarantine measures was characterized by a predominance of familialinfection and a significant proportion of unexplained extracurricular sources of infectionin children. In most infants with coronavirus disease caused by the new SARS-CoV-2coronavirus, respiratory symptoms were dominated by signs of upper respiratory tractinvolvement.

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Presence and Duration of Symptoms in Febrile Infants With and Without SARS-CoV-2 Infection

Cited by 7 publications

References 6 publications

COVID-19 clinical features in primary care: COVIDPAP study

COVID-19 clinical features in primary care: COVIDPAP study

A Term Infant Presenting with COVID-19 Disease at Birth and a Croup-Like Cough

Clinical and Epidemiological Peculiarities if Covid-19 Infection in Infants

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