Presença extra-intestinal de cistos unizóicos de Isospora belli em paciente com SIDA: relato de caso

Abstract

This report describes the presence of Isospora belli unizoic cysts in mesenteric lymph nodes and of gametocytes in the gallbladder epitelium of a 26 year-old Brazilian male patient with Acquired Immune Deficiency Syndrome. This patient had received treatment for several times with sulfamethoxazole-trimethoprim. It is discussed the significance of I. belli tissue cysts as possible foci of resistance of the parasite and their association with the infection relapse even post-treatment with anticoccidian medication.

Cistoisosporíase: breve revisão clínica

“…O quadro pode ser de diarreia profusa, com número superior a oito evacuações diárias. Pode ocorrer perda de peso, dor abdominal em cólica, vômito e desidratação, necessitando, em muitos casos, de hospitalização (FRENKEL et al, 2003).…”

Determination of the genera of cyst-forming coccidia

“…C. belli shed in human feces forms unizoic cysts in extra-intestinal tissues of humans, the definitive host (Lindsay et al 1997;Frenkel et al 2003); their intermediate host has not been identified. These species were described originally in the genus Isospora, in the belief that they were monoxenous organisms.…”

Molecular characterization of Cystoisospora belli and unizoite tissue cyst in patients with Acquired Immunodeficiency Syndrome

“…In patients with the acquired immunodeficiency syndrome (AIDS) it has been described as another opportunistic agent that can cause chronic diarrhoea, acalculous cholecystitis and cholangiopathy (Benator et al 1994; Zenta and Topazian, 2009). Reports of disseminated cystoisosporosis with unizoite tissue cysts in the lamina propria of the intestines, lymph nodes, liver and spleen in patients with AIDS have been published (Comin and Santucci, 1994; Restrepo et al 1987; Michiels et al 1994; Velasquez et al 2001; Frenkel et al 2003). The Cystoisospora felis species infects cats and several hosts (Dubey and Frenkel, 1972; Costa and Lopes, 1998; Melo et al 2003).…”