Prescription pattern of ocular hypotensive drugs in Portugal and its comparison with the European guidelines – <scp>PEM</scp> Study

Pimenta, Gonçalo; Sousa, David Cordeiro; Leal, Inês; Marques‐Neves, C.; Pinto, Luís Abegão

doi:10.1111/aos.14103

Cited by 4 publications

(3 citation statements)

References 4 publications

(4 reference statements)

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“…PGAs were the most prescribed therapeutic group, especially in elderly individuals, which is consistent with other studies (48.0–58.8%) [ 16 , 20 , 25 , 32 , 33 ], but higher than that found in Taiwan and China (22.8% and 30.2%, respectively) [ 22 , 24 ]. Similarly, the most prescribed drug was latanoprost, as evidenced in other studies (28.0–50.0%) [ 20 , 24 , 34 ].…”

Section: Discussionsupporting

confidence: 91%

“…Combination therapy with antiglaucoma agents predominated in this report, contrasting with other pharmacoepidemiological investigations where monotherapy prevailed (54.0–78.4%) [ 20 , 22 , 32 , 33 ]. This is probably due to the methodological differences used in the studies (e.g., type of study, way of identifying the cases, characteristics of the patients) [ 20 , 22 , 32 , 33 ], as our group of patients may have had a greater severity of the pathology. In this sense, men and increasing age have been associated with a greater risk of blindness and vision loss [ 31 ].…”

Section: Discussioncontrasting

confidence: 72%

“…Similarly, the most prescribed drug was latanoprost, as evidenced in other studies (28.0–50.0%) [ 20 , 24 , 34 ]. BB were also used with high frequency in this study, which was higher than that reported in the literature (9.4–44.1%) [ 16 , 22 , 32 , 33 ]. However, in general, the pattern of use of antiglaucoma agents is in line with the recommendations of the clinical practice guidelines, which suggest PGA as the first line of treatment or, failing that, BB [ 6 , 7 , 8 ].…”

Section: Discussionmentioning

confidence: 82%

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Use Pattern of Ophthalmic Antiglaucoma Agents with and without Preservatives: A Cross-Sectional Study

et al. 2023

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Background: Different drugs have been approved to reduce the intraocular pressure. However, most of them contain preservatives to maintain sterility and these can be toxic to the ocular surface. The aim was to determine the patterns of use of antiglaucoma agents and ophthalmic preservatives in a group of patients from Colombia. Methods: A cross-sectional study that identified ophthalmic antiglaucoma agents from a population database of 9.2 million. Sociodemographic and pharmacological variables were considered. Descriptive and bivariate analyses were performed. Results: A total of 38,262 patients were identified, with a mean age of 69.2 ± 13.3 years, and 58.6% were women. A total of 98.8% were prescribed antiglaucoma drugs in multidose containers. The most widely used were prostaglandin analogs (59.9%), especially latanoprost (51.6%) and β-blockers (59.2%). A total of 54.7% of patients received combined management, especially with fixed-dose combination (FDC) drugs (41.3%). A total of 94.1% used antiglaucoma drugs with preservatives (benzalkonium chloride, 68.4%). Conclusions: The pharmacological treatment of glaucoma was very heterogeneous, but the most commonly used therapeutic groups were in accordance with the recommendations of clinical practice guidelines but with differences by sex and age. Most of the patients were exposed to preservatives, especially benzalkonium chloride, but the wide use of FDC drugs can minimize toxicity on the ocular surface.

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Section: Discussionsupporting

confidence: 91%

Section: Discussioncontrasting

confidence: 72%

Section: Discussionmentioning

confidence: 82%

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Use Pattern of Ophthalmic Antiglaucoma Agents with and without Preservatives: A Cross-Sectional Study

et al. 2023

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Glaukomversorgung in Deutschland – Ergebnisse einer Mitglieder-Umfrage von DOG und BVA: Teil 2: Therapie

Wolfram

Schuster

2022

Ophthalmologie

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Zusammenfassung Hintergrund Die Therapieoptionen beim Glaukom sind vielfältig. Das ruft die Frage hervor, welche Verfahren sich in der Alltagsversorgung als praktikabel und sinnvoll erweisen. Unter den Mitgliedern der Deutschen Ophthalmologischen Gesellschaft (DOG) und des Berufsverbands der Augenärzte Deutschlands (BVA) wurde eine anonymisierte Befragung durchgeführt, um die aktuelle Versorgungspraxis für Deutschland abzubilden. Ziel der Arbeit Diese Publikation gibt ein Meinungsbild unter der deutschen Augenärzteschaft wieder zur aktuellen Glaukomversorgung, Therapiestrategien und der Rolle der Glaukomchirurgie. Material und Methoden Die Befragung wurde durch einen Online-Fragebogen mit 26 Fragen (107 Antwort-Items) zur praktizierten Glaukomversorgung durchgeführt. Vollständige Fragebögen lagen von 1361 Personen vor. Ergebnisse 84,8 % der Befragten formulieren einen Zieldruck „häufig“ bis „eher häufig“. Einen systemischen Therapieansatz verfolgen 44,9 %. Zwei Drittel der Befragten stellen eine Beeinträchtigung der Lebensqualität durch Nebenwirkungen von Augentropfen fest, wovon konjunktivale Rötung und Brennen am häufigsten sind. Durchschnittlich schätzen Augenärzte 32 % der Patienten als non-adhärent in ihrer Therapie ein. Bei 5–10 % der Patienten erfolgt eine glaukomchirurgische Therapie. Unter den interventionellen Therapieverfahren halten über 90 % die Trabekulektomie für sinnvoll, gefolgt von minimal-invasiven Operationsverfahren (MIGS) und der selektiven Lasertrabekuloplastik (SLT). MIGS und SLT werden jedoch am häufigsten durchgeführt. Schlussfolgerung Bei der Wahl der Therapieoption gilt es, die gewünschte Dauerhaftigkeit der Drucksenkung mit der Praktikabilität und Zumutbarkeit der Verfahren zu harmonisieren. Dem Wunsch nach mehr Übersicht und Struktur der Glaukomversorgung sollte Rechnung getragen werden.

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Anwendung von Antiglaukomatosa in der urbanen erwachsenen Bevölkerung

Wolfram,

Vu,

Klemm

et al. 2023

Ophthalmologie

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Prescription pattern of ocular hypotensive drugs in Portugal and its comparison with the European guidelines – PEM Study

Cited by 4 publications

References 4 publications

Use Pattern of Ophthalmic Antiglaucoma Agents with and without Preservatives: A Cross-Sectional Study

Use Pattern of Ophthalmic Antiglaucoma Agents with and without Preservatives: A Cross-Sectional Study

Glaukomversorgung in Deutschland – Ergebnisse einer Mitglieder-Umfrage von DOG und BVA: Teil 2: Therapie

Anwendung von Antiglaukomatosa in der urbanen erwachsenen Bevölkerung

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