Prescription pattern of antidepressants in five tertiary care psychiatric centres of India

Desousa, Avinash; Bhagabati, Dipesh; Shah, Nilesh; Kallivayalil, Roy Abraham; Grover, Sandeep; Jk, Trivedi; Shinfuku, Naotaka

doi:10.4103/0971-5916.184289

Cited by 37 publications

(29 citation statements)

References 17 publications

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“…Total of 56 study subjects having co-morbidities along with depression were included this study. Most of the subjects (26.79%) were found to have hypertension, followed by 25% subjects with diabetes mellitus which is similar to the study conducted by Adarsh Tripathi et al, where most of the subjects (5.78%) were found to have Diabetes Mellitus (Tripathi et al, 2016).…”

Section: Distribution Of Subjects Based On Medication Adherencesupporting

confidence: 87%

Assessment of severity, quality of life and suicidal ideation in patients with depressive disorders

D¹,

Shreeharsha²,

Akshay³

et al. 2020

ijrps

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Depression is estimated to be the third leading cause of disability and about 350 million people suffer from depression worldwide. Various biological, social, economic, cultural factors and environmental factors contribute for depression. A total of 102 patients were enrolled in the study. Majority of the patients (64, 62.74%) included in the study were female. The mean age of the study subjects was found to be 20.4±11.88 years. The severity of symptoms in depressed patients evaluated using Hamilton Depression Rating Scale (HDRS) shows that 33.33% of the subjects were very severely depressed, followed by 29.41% of the subjects with moderate depression, 23.52 % with severe depression and 11.76% with mild depression. Quality of life was evaluated using WHOQOL BREF Scale in the study population. 51.96 % of subjects were having low quality of life (QoL) followed by 48% of subjects with medium QoL and 0.98% subjects with high QoL. Modified Scale for Suicidal Ideation (MSSI) was used to evaluate severity of suicidal ideation in study population. Interpretation of results shows that 74.50% were having low suicidal ideation and few subjects (8.82%) were found to have severe suicidal ideation. Depression negatively impacts individual’s functioning, work satisfaction, relationships, leisure, physical and mental health, sexual functioning, sleep patterns and overall sense of fulfilment and contentment with life. Severe form of depression can lead to suicidal risk, increased risk of morbidity, mortality, substantial imbalance on individual’s occupational potential, significant physical and psychosocial impairment.

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Section: Distribution Of Subjects Based On Medication Adherencesupporting

confidence: 87%

Assessment of severity, quality of life and suicidal ideation in patients with depressive disorders

D¹,

Shreeharsha²,

Akshay³

et al. 2020

ijrps

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“…Overall, 272 (87.18%) patients were using newer antidepressants. 13 Boulenger JP et al compared efficacy of long-term treatment with escitalopram and paroxetine in severely depressed patients and found that escitalopram as significantly more effective than paroxetine in the long-term treatment of severely depressed patients. 14 The above studies indicate that use of SSRIs is much more common in comparison to other group of antidepressant drug for the management of depression and other psychotic disorders.…”

Section: Discussionmentioning

confidence: 99%

A drug utilization study of antidepressant drugs in a tertiary care hospital

Yerkade

Siddiqui

2017

Int J Basic Clin Pharmacol

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Background: In psychiatric practice, antidepressant drugs are widely used group of drugs. Number of drugs are available in this group with diverse type of mechanisms and efficacy/safety profile. The objective for the study was to identify the prescribing pattern of antidepressant drugs in psychiatric patients at a tertiary care hospital and to see the distribution of antidepressant drugs in the sociodemographic group.Methods: It was a record based descriptive study which was carried out at NKP Salve Institute of Medical Sciences and Research Centre, Nagpur. Case record files of all the patients suffering from depression and other psychiatric disorders and treated with antidepressant drugs during the period of from 1st January 2015 to 31st December 2015 by institutional psychiatrists were analyzed for prescription pattern of antidepressant drugs and their age and sex wise distribution.Results: A total no. of 300 patients received antidepressant drugs. The most commonly prescribed drug was escitalopram in 121 (40.3%) patients followed by fluoxetine in 61 (20.3%) and clomipramine in 30 (10%) patients. Other drugs that were prescribed were mirtazapine in 24 (8%), nortryptiline in 21 (7%), venlafaxine in 13 (4.3%), fluvoxamine in 12 (4%), amitryptiline in 9 (3%), dothiepin in 5 (1.6%) and duloxetine in 4 (1.3%) patients. Also patients in the age group of 31-40 yrs and 21-30 yrs received most number of antidepressants i.e. 129 (40.3%) and 83 (27.6%) patients respectively. Females have received more antidepressant drugs as compared to males.Conclusions: Selective Serotonin Reuptake Inhibitors (SSRIs) are the most commonly prescribed group of antidepressant drugs. Escitalopram followed by Fluoxetine were the most commonly prescribed drugs for the management of depression and other psychiatric disorders because of their better efficacy, safety, tolerability and less side effects as compared to TCAs. Females suffer more from depression and other psychiatric disorders as compared to males and the most vulnerable is 21 to 40 yrs of age.

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“…This survey showed that SGA’s are the main antipsychotic drugs for the treatment of Schizophrenia in Asia 3. Another survey on the use of antidepressants was conducted in 2014 by East Asia and South Asia 4,5…”

Section: Introductionmentioning

confidence: 97%

Changing trends in anti-psychotic prescription pattern in Pakistan

Malik

Ghani²,

Mazhar³

et al. 2019

Pak J Med Sci

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Background and Objective: This study was designed to identify the changing trends in Antipsychotic prescription pattern in Pakistan. It was part of the research project Research on East Asian Psychotropic Prescription Pattern (REAP) carried out to identify the prescription patterns of schizophrenic patients in different countries located in Asia. Our objective was to assess the trend and change of psychotropic drug prescriptions for patients with schizophrenia. Methods: The design of the study was quantitative and of descriptive epidemiology. This study was carried out from 30th March 2017. Data was collected on a unified protocol by the Psychiatrists from Pakistan. Three (3) centers i.e., Lahore, Karachi and Islamabad provided the data. Indoor and outdoor cases with Schizophrenia were recruited. A web based recording system for collection of data done at Taipei Taiwan, and statistical analysis was performed and transferred to all participating centers including Pakistan. Results: The main findings of the study were that majority of the patients were prescribed antipsychotic poly pharmacy drug. It was also found that Anxiolytics, anti-depressants and Antiparkinsonian drugs were also co-prescribed. Conclusion: It was concluded that antipsychotic poly pharmacy along with Anxiolytics, anti-depressants and Anti-parkinsonian drugs were prescribed to patients with schizophrenia in Pakistan. doi: https://doi.org/10.12669/pjms.35.3.136 How to cite this:Malik M, Ghani MU, Mazhar W, Munir N. Changing trends in anti-psychotic prescription pattern in Pakistan. Pak J Med Sci. 2019;35(3):---------. doi: https://doi.org/10.12669/pjms.35.3.136 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Prescription pattern of antidepressants in five tertiary care psychiatric centres of India

Cited by 37 publications

References 17 publications

Assessment of severity, quality of life and suicidal ideation in patients with depressive disorders

Assessment of severity, quality of life and suicidal ideation in patients with depressive disorders

A drug utilization study of antidepressant drugs in a tertiary care hospital

Changing trends in anti-psychotic prescription pattern in Pakistan

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