Prescription pattern of antibiotics in neonatal intensive care unit of tertiary care hospital

Baig, Shiraz Mirza; Naikwadi, Imran B.; Deshmukh, L. S.

doi:10.18203/2319-2003.ijbcp20190152

Cited by 3 publications

(1 citation statement)

References 7 publications

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“…Around 28% of global population consists of children and newborns. 1 They are more likely to suffer from acute watery diarrhoea, viral fever, and recurring illnesses of the respiratory tract and gastrointestinal system, which account for the bulk of paediatric visits. Lower respiratory tract infections are the primary cause of mortality in children under the age of five, making it necessary to accurately diagnose the condition and give appropriate drug therapy.…”

Section: Introductionmentioning

confidence: 99%

Study of Drug Prescribing Pattern in Pediatric Outpatient Department at a Tertiary Care Teaching Hospital

Rahul¹,

Sravya²,

Hiremath³

2021

J. Drug Delivery Ther.

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Background: Infants and children suffer from frequent but usually non serious illnesses and are more vulnerable to various adverse events related to drugs and poor understanding of instructions on prescription by the patient or caretakers were likely to cause medication error. The correct identification of an illness and its management with medications is a vital aspect of patient care, especially for paediatric population. So, prescribing pattern studies are very helpful in promoting the appropriate use of drugs in population. Objectives: It aims to obtain data on the current prescribing pattern in pediatric OPD at a tertiary care teaching hospital with ultimate goal to promote appropriate use of drugs. Methods: This study was conducted in 62 pediatric patients of either sex visiting Pediatric out-patient department over a period of three months at NMCH and RC, Raichur, Karnataka. Results: Prescription analysis showed that the average number of drugs per prescription was 3.32. Drugs were mostly prescribed by brand name (98.06%), Injections (4.83%) were least prescribed, drugs prescribed from Essential Drug List was 48.54%. Antibiotics were most prescribed class of drugs (33.9%). Conclusion: The study concludes that polypharmacy was slightly seen in prescriptions. Diagnosis of the patient was recorded for most of the prescriptions. There is need to conduct many such studies at regular interval as it is useful for auditing large number of prescriptions to find out early signals of the irrational drug use. Our study evaluated drug use pattern only from the outpatients hence prescription pattern may vary among inpatients. Keywords: Prescribing pattern, Infants, WHO core prescribing indicators, Polypharmacy, Generic name

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Section: Introductionmentioning

confidence: 99%

Study of Drug Prescribing Pattern in Pediatric Outpatient Department at a Tertiary Care Teaching Hospital

Rahul¹,

Sravya²,

Hiremath³

2021

J. Drug Delivery Ther.

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Retracted: Drug Utilization Pattern of Antibiotics in Neonatal intensive care unit in a Tertiary Care Hospital, India

G Doddawad

2024

Ross. vestn. perinatol. pediatr.

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Millions of babies are admitted to neonatal intensive care units worldwide, with a significant proportion facing various indications. Given that sepsis is a leading cause of mortality and morbidity among infants globally, including in India, the importance of efficient antibiotic use cannot be overstated. As the global problem of drug resistance intensifies, prudent antibiotic usage becomes crucial in mitigating treatment failures and ensuring the survival of newborns. Aim: to evaluate the pattern of antimicrobial drug utilization in neonatal intensive care unit (NICU) to assess the criteria for drug selection in tertiary care hospital.Materials and Methods. It was an observational prospective study conducted for six months in which 200 neonates admitted to neonatal intensive care unit at tertiary care Hospital, were included. Demographic details, duration of hospital stay, reason for admission (disease pattern), various drugs prescribed were noted. Results. Out of 200 neonates the number of male babies admitted to neonatal intensive care unit were 115 (57.5%) and female babies were 85 (42.5%). Many of the neonates were from age group of 1 to 5 (58.5%) days. Most of the neonates were from weight group of 2.5 to 3 (26.5%) kg. Majority of neonates hospital admission duration was 3 to 6 days is 98 (49%) neonates. Most common disorder requiring neonatal intensive care unit admission was Preterm with Respiratory Distress Syndrome (29%) followed by Neonatal Sepsis (19.5%) and Preterm (11%). Other distress reported include birth asphyxia (16 neonates or 8%), Neonatal convulsions (12 neonates or 6%), Late preterm (13 neonates or 6.5%), Hypernatremia (9 neonates or 4.5%), Meconium Aspiration Syndrome (3 neonates or 1.5%), Neonatal Hypoglycemia (5 neonates or 2.5%) and others (23 neonates or 11.5%). Among 423 antibiotics most prescribed antibiotic was Inj. Piperacillin + Tazobactam (35.4%) followed by Gentamycin (30.2%). Out of 423 drugs 152 are fixed dose combination and single drugs are 271 in this study in which piperacillin + tazobactam of fixed dose combination and gentamicin dose combination and single drugs are 271 in this study in which piperacillin + tazobactam of fixed dose combination and gentamicin of single drug had prescribed in more amount.Conclusion. The findings of this study will contribute to the existing body of knowledge regarding the appropriate use of antibiotics in the NICU, thereby providing insights for healthcare professionals to make informed decisions regarding antibiotic therapy. Empirical antibiotics were administered to every newborn based on their individual conditions. The antibiotic utilization pattern within this study group was determined to be rational.

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Drug Utilization Pattern of Antibiotics in Neonatal Intensive Care Unit at a Tertiary Care Hospital, Mysuru, Karnataka

Pushpa,

Pallda,

Sudharman

et al. 2023

Asian Journal of Pharmaceutical Research and Health Care

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Introduction: Millions of babies are admitted to neonatal intensive care units (ICUs) worldwide, with a significant proportion facing various indications. Given that sepsis is a leading cause of mortality and morbidity among infants globally, including in India, the importance of efficient antibiotic use cannot be overstated. As the global problem of drug resistance intensifies, prudent antibiotic usage becomes crucial in mitigating treatment failures and ensuring the survival of newborns. Aim: The aim of this study was to evaluate the pattern of antimicrobial drug utilization in neonatal intensive care unit (NICU) to assess the criteria for drug selection in a tertiary care hospital. Materials and Methods: It was an observational, prospective study conducted for 6 months in which 200 neonates admitted to the NICU at a tertiary care hospital were included in the study. Results: Out of 200 neonates, the number of male babies admitted to NICU was 115 (57.5%) and female babies were 85 (42.5%). Many of the neonates were from the age group of 1 to 5 days (58.5%). Most of the neonates were from the weight group of 2.5 to 3 kg (26.5%). The hospital admission duration for the majority of neonates is within the 3–6-day range, accounting for 98 neonates, which represents 49% of the cases. The most prevalent reason for admission to the neonatal ICU (NICU) was preterm with respiratory distress syndrome, comprising 29% of cases, followed by neonatal sepsis at 19.5%, and preterm births at 11%. Among 423 antibiotics, the most prescribed antibiotic was injection piperacillin + tazobactam (35.4%) followed by gentamicin (30.2%). Conclusion: Empirical antibiotics were administered to every newborn based on their individual conditions. The antibiotic utilization pattern within this study group was determined to be rational.

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Prescription pattern of antibiotics in neonatal intensive care unit of tertiary care hospital

Cited by 3 publications

References 7 publications

Study of Drug Prescribing Pattern in Pediatric Outpatient Department at a Tertiary Care Teaching Hospital

Study of Drug Prescribing Pattern in Pediatric Outpatient Department at a Tertiary Care Teaching Hospital

Retracted: Drug Utilization Pattern of Antibiotics in Neonatal intensive care unit in a Tertiary Care Hospital, India

Drug Utilization Pattern of Antibiotics in Neonatal Intensive Care Unit at a Tertiary Care Hospital, Mysuru, Karnataka

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