2019
DOI: 10.1016/j.drugpo.2018.10.013
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Prescription opioids: Regional variation and socioeconomic status – evidence from primary care in England

Abstract: BackgroundThis study aimed to quantify dispensed opioid prescriptions among primary care practices throughout England and investigate its association with socioeconomic status (SES). MethodsThis cross-sectional study used publicly available data in 2015, including practice-level dispensing data and characteristics of registrants from the United Kingdom (UK) National Health Service Digital, and Index of Multiple Deprivation (IMD) data from Department of Communities and Local Government. Practices in England whi… Show more

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Cited by 34 publications
(61 citation statements)
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References 33 publications
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“…Furthermore, the choice of treatment can be affected: hard-pressed clinicians in poor areas, with little recourse to alternative treatments, might be more likely to prescribe medicines. 54 Our findings should be considered in the context of several limitations. First, the primary function of the NHSBSA database is to reimburse retail pharmacies for their medication purchasing and dispensing costs, rather than for population epidemiology of prescribing for particular conditions; our estimates include, for example, opioids given appropriately in terminal care to patients (other than those recorded in the cancer registration dataset) and gabapentinoids necessarily used in the long term for epilepsy.…”
Section: Discussionmentioning
confidence: 87%
“…Furthermore, the choice of treatment can be affected: hard-pressed clinicians in poor areas, with little recourse to alternative treatments, might be more likely to prescribe medicines. 54 Our findings should be considered in the context of several limitations. First, the primary function of the NHSBSA database is to reimburse retail pharmacies for their medication purchasing and dispensing costs, rather than for population epidemiology of prescribing for particular conditions; our estimates include, for example, opioids given appropriately in terminal care to patients (other than those recorded in the cancer registration dataset) and gabapentinoids necessarily used in the long term for epilepsy.…”
Section: Discussionmentioning
confidence: 87%
“…Income quintile. Income, material deprivation, and socio-economic status have been linked to higher rates of OUD [45][46][47]. Since income can have a significant impact on health, it was included as a potential correlate.…”
Section: Plos Onementioning
confidence: 99%
“…This might be supported by regional variations of the residents' socioeconomic status, which was shown to have an influence on opioid use in international studies. 17,36,37 In Germany, districts categorized as peripheral or very peripheral, 24 where opioid use was high, largely overlap with areas displaying lower socioeconomic indicators (measured by education, occupation and income). These areas are, for example, located in Saarland, North Rhine-Westphalia, in rural areas of Lower Saxony and in the east of Germany.…”
Section: Potential Reasons For Regional Variationsmentioning
confidence: 99%
“…For Europe a more than 10-fold difference was observed between the highest consumption in Western/Northern countries and the lowest in Southern/ Eastern countries. 7 Besides differences between countries, regional variations in opioid utilization are known for example from the United States, the United Kingdom or Australia 8,[16][17][18][19] listing, among others, ruralness and lower social economic status as influencing factors for higher opioid consumption.…”
Section: Introductionmentioning
confidence: 99%