2013
DOI: 10.5694/mja12.11683
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Prescribing trends before and after implementation of an antimicrobial stewardship program

Abstract: The introduction of an antimicrobial stewardship program, including postprescription review, resulted in an immediate reduction in broad-spectrum antimicrobial use in a tertiary referral centre. However, the effect of this intervention reduced over time.

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Cited by 51 publications
(54 citation statements)
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“…Even though TQC reform does not mandate early management and patient care is expected to be undertaken using the same clinical standards following complete assessment, a potential adverse effect may be rapid antibiotic prescribing without consideration to full patient assessment. Appropriateness of antibiotic prescription therefore presents another performance measure, and further improvements in both appropriateness and timing need broader evaluation and may be achieved through the use of stewardship programmes …”
Section: Discussionmentioning
confidence: 99%
“…Even though TQC reform does not mandate early management and patient care is expected to be undertaken using the same clinical standards following complete assessment, a potential adverse effect may be rapid antibiotic prescribing without consideration to full patient assessment. Appropriateness of antibiotic prescription therefore presents another performance measure, and further improvements in both appropriateness and timing need broader evaluation and may be achieved through the use of stewardship programmes …”
Section: Discussionmentioning
confidence: 99%
“…Operational models of infectious diseases units vary from consultation-only to those focused on inpatients (e.g. The relatively low proportion of referrals from ICU may in part be explained by the lower number of ICU beds in hospitals in our region [11], and the provision of ID services on routine ICU rounds, which were not included in this survey [12]. In Australia, where infectious diseases services are relatively mature, most larger hospitals have a mix of both consultations and inpatients, whereas in smaller hospitals consultative services predominate.…”
Section: Discussionmentioning
confidence: 99%
“…Of note, all nine studies applied restriction mainly in lastresort antibiotics, including third-generation or fourth-generation cephalosporins, vancomycin, tigecycline, linezolid, imipenem, meropenem, and fluoroquinolones (Table 1). If we take into consideration the three studies that we excluded since they reported exclusively the change in consumption of restricted antibiotics (53)(54)(55). the pooled decrease in the consumption was 25% (95% CI ϭ 34.2 to 15.8, 2 ϭ 0.02, Egger's bias ϭ Ϫ1.84, P ϭ 0.560).…”
Section: Resultsmentioning
confidence: 99%