“…For children with kidney failure, the ISPD guideline provides guidance on the timing of initiation of longterm dialysis, selection of dialysis modality, and assessment and management of volume status and solute clearances. 107 As in adults, the timing of dialysis initiation is a complex decision that requires an assessment of uremic signs and symptoms, fluid overload, and biochemical abnormalities. 18,108 In addition, suboptimal growth and development should influence the timing of dialysis initiation in children.…”