Prescribing pattern of antimicrobial agents in pediatrics department of a teaching hospital

Mohapatra, Satyakam; Tripathy, Saswati; Chandrasekar, Balaji; Rani, Raj; Sekar, P.

doi:10.18203/2319-2003.ijbcp20150385

Cited by 5 publications

(6 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the present study, the total percentage of male patients was 89 (55.62%) as compared to the 71 (44.38%) of female patients which were similar to the studies conducted by Mohapatra S et al and Mathai D et al 10,11 Antimicrobials were found to be given more to children in the age group of 6-12 years 64 (40.00%) The matter of worry is that many surgeons worldwide simply accept the fact that organs are even being reported to be removed to manage the infection spread, due to the high rate of antibiotic resistance in some patients.…”

Section: Discussionsupporting

confidence: 91%

Untitled

2022

IJPSR

View full text Add to dashboard Cite

This study gives an overview of prescribing pattern of antibiotics in children in our tertiary care teaching hospital. Methods: It is a prospective observational study carried out on paediatric in-patients with a sample of 160 patients based on age, inclusion, and exclusion criteria for a period of 6 months. The patient's data were collected using a patient case record form and the data analysis was done. Results: Out of 160 patients data that were collected, the results showed that the majority of gender which were admitted to the hospital were male children 89 (55.62%), and many were from the age group of early childhood (6-12 years) 64 (40.00%). Respiratory tract infections were the diagnosis most commonly analyzed; overall, 236 prescribed antibiotics, cephalosporins 121 (51.21%) were commonly evident, and parenteral 161 (68.22%) -route of administration was observed to be followed more than other routes. Conclusion: Antibiotic Resistance is a worrisome factor worldwide, challenging treatment regimens. Surgeons & Physicians worldwide find it difficult to cope with the increased resistance patterns and design dosing regimens accordingly. This study analyzes the prescribing pattern trend of antibiotics in our hospital and drives a conclusion about antibiotic usage.

show abstract

Section: Discussionsupporting

confidence: 91%

Untitled

2022

IJPSR

View full text Add to dashboard Cite

show abstract

“…In this study it was found that 40.4% children belonged to the age group of less than 5 years, similar findings were recorded in studies by Kokani et al, Malpani et al, Tiwari et al and Mahapatra et al [10][11][12][13] This large number is perhaps because the children in this age group are more susceptible to infection, mainly due to weaning causing reduction in their immunity and getting exposed to the outside environment more often. In the present study, 2/3 rd children screened were from the outpatient department whereas 1/3 rd were from the pediatric ward.…”

Section: Discussionsupporting

confidence: 87%

“…The studies conducted by Kokani et al, Majhi et al and Baidya et al reported injectables as the major route of drug administration. 7,10,[12][13][14][15] It could be possibly because these studies had more cases of LRTI and use of injectables was appropriate considering the indication. 10,11,16,17 The use of penicillins was predominant as it is the safest antibiotic in this population and is also recommended by the American academy of pediatrics and National centre for disease control in India pertaining to antimicrobial use in pediatric population.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of prescription pattern of antimicrobials in the treatment of respiratory tract infections in pediatric patients attending a tertiary care hospital

Patel

Sapra²,

Bhave³

et al. 2023

Int J Basic Clin Pharmacol

View full text Add to dashboard Cite

Background: Irrational use of antimicrobials is a complex and multifactorial problem in developing countries. Prescriptions not adhering to the treatment guidelines, self-medication, inappropriate use of drugs by patients can inadvertently lead to development of antimicrobial resistance. An observational study was designed to evaluate antimicrobial use in pediatric population with respiratory tract infections and its adherence to national treatment guidelines. Methods: This was a cross sectional observational study initiated after taking institutional ethics committee permission. The prescriptions of children diagnosed with upper respiratory tract infections and lower respiratory tract infections (LRTI) were screened. Their demographic profile and details of drugs prescribed were recorded. Results: Out of 230 pediatric prescriptions,155 (67%) were from outpatient department and 75 (33%) from those admitted in ward. Total 145 children were diagnosed with URTI whereas 85 had LRTI. In this study, 60 children with URTI received combination of amoxicillin and clavulanic acid (Co-amoxiclav) whereas 66 children with LRTI received Co-amoxiclav,18 ceftriaxone (N=18), 6 vancomycin (N=6) and 18 were prescribed oseltamivir (N=18), either alone or in combination. Other drugs prescribed included, paracetamol for fever and cough syrups. Out of 195 drugs prescribed by brand names, 138 (70.8%) were antimicrobials. Fixed dose combination amoxicillin and clavulanic acid, paracetamol and cough syrups were available from hospital pharmacy. None of the prescriptions had polypharmacy. Conclusions: URTI was treated using single antimicrobial whereas LRTI was treated with more than one antimicrobials or combination of antimicrobial and antiviral agent. The prescriptions were in accordance with the national treatment guidelines.

show abstract

“…Single antibiotic therapy was prescribed in most of the prescriptions (77.87%) which is similar to the study done by Mohapatra et al [17] and Arute et al [18] and the average number of antibiotics per prescriptions was 1.25±0.62. In our study, according to antibiotics prescribed as per the diagnosis, amoxicillin-clavulanic acid was most common antibiotic given in cases of acute bronchiolitis and WALRI whereas cefotaxime and sulfisoxazole and trimethoprim combination in pneumonia and hyperactive airway disease, respectively, which is similar to Shruthi et al [13].…”

Section: Discussionsupporting

confidence: 84%

A Prescription Pattern Study of Respiratory Tract Infections in Paediatric Indoor Patients in a Tertiary Care Teaching Hospital - A Prospective Observational Study

Badar

Parulekar

Garate

2018

Asian J Pharm Clin Res

View full text Add to dashboard Cite

Objectives: The objectives of the study were as follows: (1) To study the prescription patterns in Respiratory tract infections (RTI) in indoor patients in pediatric wards. (2) To check the rationality of treatment according to Modified Kunin’s rationality criteria. (3)To analyze the data of RTI by Anatomical Therapeutic Chemical classification.Methods: It was a non-interventional, prospective, observational study which was conducted in indoor pediatric patients in a tertiary care teaching hospital in India. Data were analyzed and evaluated according to the WHO rational use of drugs guidelines.Study sample: The study sample was 174.Study duration: The study duration was August 15, 2016–September 15, 2016.Results: Males (63.79%) were more as compared to females (36.20%), and the highest number of cases was seen in infants (62.06%). Acute bronchiolitis (54.02%) was highest in the incidence followed by Wheeze Associated Lower Respiratory Tract Infection (WALRI) (30.45%). The average duration of patient stay in hospital was 4.71 days whereas 93.33% were polytherapy and mostly prescribed antibiotic was amoxicillin-clavulanic acid in acute bronchiolitis and WALRI. Salbutamol (40.84%) and Ipratropium Bromide (39.43%) were the commonly prescribed respiratory medicines. Oral route (42.27%) was the most common route of administration. 56.11% drugs were prescribed by generic name.Conclusion: Standard treatment guidelines for the treatment of RTI need to be urgently developed and strictly implemented.

show abstract

Prescribing pattern of antimicrobial agents in pediatrics department of a teaching hospital

Cited by 5 publications

References 4 publications

Untitled

Untitled

Evaluation of prescription pattern of antimicrobials in the treatment of respiratory tract infections in pediatric patients attending a tertiary care hospital

A Prescription Pattern Study of Respiratory Tract Infections in Paediatric Indoor Patients in a Tertiary Care Teaching Hospital - A Prospective Observational Study

Contact Info

Product

Resources

About