Preperitoneal ropivacaine infusion versus epidural ropivacaine–morphine for postoperative analgesia in dogs undergoing ovariohysterectomy: a randomized clinical trial

Morgaz, Juán; Latorre, David F.; Serrano-Rodríguez, Juan Manuel; Granados, Miguel Ángel Núñez; Domínguez, Juan M.; Fernández-Sarmiento, José Andrés; Quirós‐Carmona, Setefilla; Navarrete‐Calvo, Rocío

doi:10.1016/j.vaa.2021.04.009

Cited by 5 publications

(4 citation statements)

References 35 publications

(42 reference statements)

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“…are widely used [ 7 , 8 , 9 ]. However, over the last years, many locoregional anaesthesia techniques have been used together with systemic analgesia to obtain a multimodal approach to nociception and decrease the dose and the potential side effects of systemic analgesics and anaesthetic drugs [ 10 , 11 , 12 ]. Some locoregional anaesthetic techniques such as infiltration or splash block are very easy to be carried out and have shown good results in previous studies in small animals [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

Clinical Assessment of Introducing Locoregional Anaesthesia Techniques as Part as the Intraoperative Analgesia Management for Canine Ovariohysterectomy in a Veterinary Teaching Hospital

Viscasillas

Cañón

Hernández

et al. 2022

Animals

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This study compared four methods to provide intraoperative analgesia during canine ovariohysterectomy in a veterinary teaching hospital. A retrospective study was designed to assess the nociceptive response, cardiorespiratory stability, quality of recovery and complications of four analgesic protocols: epidural analgesia (EPIDURAL group), Quadratus Lumborum block (QLB group), Transversus Abdominis Plane block (TAP group), and just systemic analgesia (GENERAL group). Undergraduate students carried out all the loco-regional techniques under the direct supervision of a qualified anaesthetist. A total of 120 cases met the inclusion criteria and were included in the study and were distributed as follows: 22, 27, 32 and 39 cases with EPIDURAL, GENERAL, QLB and TAP groups, respectively. Data were analysed with statistical software R using different statistical methods. Significant differences among groups were defined as p < 0.05. Based on our results, all the groups needed the same number of rescue analgesia during the intra-operative period. The use of loco-regional techniques anticipated a better quality of recovery compared with the general group. The EPIDURAL group showed a statistically lower expired fraction of sevoflurane. No differences were found regarding complications. In conclusion, these four analgesic methods are suitable and safe to be performed for canine ovariohysterectomy, although loco-regional techniques might have some advantages.

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Section: Introductionmentioning

confidence: 99%

Clinical Assessment of Introducing Locoregional Anaesthesia Techniques as Part as the Intraoperative Analgesia Management for Canine Ovariohysterectomy in a Veterinary Teaching Hospital

Viscasillas

Cañón

Hernández

et al. 2022

Animals

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“…To produce a test nociceptive stimulus, the technique of pinching the space between the toes on paws or applying a pressure over a finger with a Halstead clamp or hemostat was widely used in past studies ( 16 , 17 ). Nevertheless, it is known that a mechanical stimulus (such as pinching a skin area, or a finger) causes the activation of low-threshold mechanoreceptors, making this test non-specific ( 18 ).…”

Section: Discussionmentioning

confidence: 99%

Respiratory response to finger clamping in dogs under general anesthesia: A descriptive pilot study

2022

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Aim of the studyThe aim of this study was to assess the effects of a nociceptive stimulus on respiratory variables in anesthetized dogs.Material and methodEleven dogs received acepromazine administered intramuscularly (IM) at a dose of 0.04 mg kg−1 45 mins before induction of anesthesia. Loss of consciousness was obtained with midazolam at 0.2 mg kg−1 and propofol administered at a dose of 2 mg kg−1 intravenously (IV). Orotracheal intubation was performed and anesthesia was maintained with isoflurane in 100% oxygen. Inspired (VTi) and expired (VTe) tidal volume (VT), minute volume (VM), inspiratory and expiratory time (Ti; Te) were measured and recorded twice a second by a spirometer. The Drive (VT/Ti) and Timing [Ti/(Ti+ Te)] were calculated.After stabilizing the depth of anesthesia the variables measured by the spirometer were recorded for 5 mins [T0−5-T0]. Then (T0) interdigital clamping of the hind leg was performed until a withdrawal movement was observed. If no reaction occurred, the clamp was left in place for 60s. After removal of the clamp, respiratory variables were measured continuously for another 5 mins [T0-T0+5]. At T0+5 morphine (0.2 mg kg−1 IV) was administered. Five minutes later (T0+10), a second clamp test was performed, using the same procedure. At T0+15 the data recording was stopped.ResultThe results showed a large variation in the individual values of Drive and Timing and are presented in a descriptive manner. The observation of Drive values over time showed variations following nociceptive stimuli. Drive appears to have increased only for those dogs that did not move during the stimulus, and were therefore pinched for a full 60 s. In contrast, the study of the Timing values revealed no difference between the data before and after nociceptive stimulation. However Timing seems to increase after morphine administration.ConclusionDrive remains a parameter that needs to be studied in depth to determine its sensitivity and precocity to monitor acute nociception.

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“…Regardless of the anesthetic spread, the systemic absorption of ropivacaine must be taken into consideration when analyzing the efficacy. To date, the hypothesis of the systemic absorption of the LA when performing a peripheral or interfascial loco-regional technique is debated [42][43][44][45]. The LA released in the retroperitoneal area (between the psoas minor and QL muscles) has a systemic absorption component.…”

Section: Intraoperative Considerationsmentioning

confidence: 99%

“…The ropivacaine concentration of 0.5% was chosen as a compromise between clinical effect, staining, and duration of action. In addition, ropivacaine proposed at this concentration can provide up to 6-8 h of analgesia [45,51]. For this reason and so that there was no interference with post-operative pain assessment, the authors decided to administer an anti-inflammatory drug (NSAID) after the evaluation of the pain score at T 8.…”

Section: Post-operative Considerationsmentioning

confidence: 99%

Use of Caudal Quadratus Lumborum Block with Ropivacaine as Part of an Opioid-Free Analgesic Protocol in Dogs Undergoing Orchiectomy: A Randomized Trial

Paolini,

Bucci,

Bianchi

et al. 2024

Animals

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In veterinary medicine, the use of loco-regional anesthesia techniques is increasing. The Quadratus Lumborum block (QL) is an interfascial loco-regional technique that involves the release of local anesthetic (LA) between the Quadratus Lumborum and the Small Psoas (Pm) muscle. The study aims to evaluate the effect of the QL block on reducing the total amount of opioids in dogs undergoing pre-scrotal orchiectomy. A group of 36 dogs was enrolled in a randomized blinded study. The animals were divided into two groups: 18 in the experimental group (QL) and 18 in the control group (C). The QL group received 0.4 mL kg−1 of ropivacaine 0.5% for each hemiabdomen (total amount of 3 mg kg−1 of ropivacaine, 1.5 mg kg−1 per side). The C group was brought into the operating room (OR) after receiving the same clipping as the QL group. In the intraoperative period, opioid consumption in the QL group was significantly lower than in the C group. No differences were found in the post-operative phase. No side effects were reported when performing the QL technique. The QL block performed at the level of L6 appears to be a valid approach to reducing opioid use in dogs undergoing orchidectomy with a pre-scrotal surgical approach.

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Preperitoneal ropivacaine infusion versus epidural ropivacaine–morphine for postoperative analgesia in dogs undergoing ovariohysterectomy: a randomized clinical trial

Cited by 5 publications

References 35 publications

Clinical Assessment of Introducing Locoregional Anaesthesia Techniques as Part as the Intraoperative Analgesia Management for Canine Ovariohysterectomy in a Veterinary Teaching Hospital

Clinical Assessment of Introducing Locoregional Anaesthesia Techniques as Part as the Intraoperative Analgesia Management for Canine Ovariohysterectomy in a Veterinary Teaching Hospital

Respiratory response to finger clamping in dogs under general anesthesia: A descriptive pilot study

Use of Caudal Quadratus Lumborum Block with Ropivacaine as Part of an Opioid-Free Analgesic Protocol in Dogs Undergoing Orchiectomy: A Randomized Trial

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