Preparing Communities for Nuclear Terrorism

Stewart, D L

doi:10.2172/1093920

Cited by 1 publication

(1 citation statement)

References 6 publications

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“…A 10-kiloton nuclear blast could cause acute radiation injury in >1 million people across a >10-mile radius. Large quantities of stockpiled bone marrow, cord blood, and other sources of hematopoietic stem cells could be used either to permanently replace irreparably damaged bone marrow or to serve as a ‘bridge’ until the recovery of autologous hematopoiesis 126 . The blast from such an event could cause burns and/or trauma combined with radiation exposure in over 45,000 victims 127 , necessitating skin grafts for severe burns 128,129 , and blood vessel grafts for extremity injuries 130 .…”

Section: Challenges In Complex Tissue Preservationmentioning

confidence: 99%

The promise of organ and tissue preservation to transform medicine

et al. 2017

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The ability to replace organs and tissues on demand could save or improve millions of lives each year globally and create public health benefits on par with curing cancer. Unmet needs for organ and tissue preservation place enormous logistical limitations on transplantation, regenerative medicine, drug discovery, and a variety of rapidly advancing areas spanning biomedicine. A growing coalition of researchers, clinicians, advocacy organizations, academic institutions, and other stakeholders has assembled to address the unmet need for preservation advances, outlining remaining challenges and identifying areas of underinvestment and untapped opportunities. Meanwhile, recent discoveries provide proofs of principle for breakthroughs in a family of research areas surrounding biopreservation. These developments indicate that a new paradigm, integrating multiple existing preservation approaches and new technologies that have flourished in the past 10 years, could transform preservation research. Capitalizing on these opportunities will require engagement across many research areas and stakeholder groups. A coordinated effort is needed to expedite preservation advances that can transform several areas of medicine and medical science.

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Section: Challenges In Complex Tissue Preservationmentioning

confidence: 99%