Abstract:Identifying impurities in drug substances has become one of the most important issues in pharmaceutical analysis since it can have a significant impact on the efficacy of new pharmaceutical products. Due to the purity requirements, in this paper a new synthetic α 2 -adrenoceptor agonist, called LPSF-PT-31, was purified and its impurities were characterized by liquid chromatographymultistage mass spectrometry (LC-MS n ) and liquid chromatography-solid phase extraction-nuclear magnetic resonance (LC-SPE-NMR). Th… Show more
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