“…This process inhibits the activity of α-glucosidase. 88 Following complex enzymatic hydrolysis, the polysaccharide found in sweet potato stems and leaves markedly increased the inhibition rate of αglucosidase and α-amylase, and this inhibition rate increased in a concentration-dependent manner as the polysaccharide concentration increased. Due to the enzymatic treatment, intermolecular forces and microstructures were altered along with the intermolecular aggregation state and chemical composition of polysaccharides.…”
Section: Effect Of Biological Modifications On the Hypoglycemic And H...mentioning
confidence: 99%
“…Enzymes can alleviate hypoglycemia by binding the exposed hydroxyl groups to amino acid residues in digestive enzymes by breaking the glycosidic bonds of polysaccharides. This process inhibits the activity of α-glucosidase . Following complex enzymatic hydrolysis, the polysaccharide found in sweet potato stems and leaves markedly increased the inhibition rate of α-glucosidase and α-amylase, and this inhibition rate increased in a concentration-dependent manner as the polysaccharide concentration increased.…”
Section: Effect Of Structural Modifications On the Biological
Activit...mentioning
Polysaccharides
are an important class of biomolecules derived
from several sources. However, the inherent structure of polysaccharides
prevents them from exhibiting favorable physicochemical properties,
which restricts their development in agriculture, industry, food,
and biomedicine. This paper systematically summarizes the changes
in the primary and advanced structures of modified polysaccharides,
and focuses on the effects of various modification methods on the
hydrophobicity, rheological properties, emulsifying properties, antioxidant
activity, hypoglycemic, and hypolipidemic activities of polysaccharides.
Then there is a list the applications of modified polysaccharides
in treating heavy metal pollutants, purifying water resources, improving
beverage stability and bread quality, and precisely delivering the
drug. When summarized and reviewed, the information above can shed
further light on the relationship between polysaccharide structure
and function. Determining the structure–activity relationship
provides a scientific basis for the direction of molecular modifications
of polysaccharides.
“…This process inhibits the activity of α-glucosidase. 88 Following complex enzymatic hydrolysis, the polysaccharide found in sweet potato stems and leaves markedly increased the inhibition rate of αglucosidase and α-amylase, and this inhibition rate increased in a concentration-dependent manner as the polysaccharide concentration increased. Due to the enzymatic treatment, intermolecular forces and microstructures were altered along with the intermolecular aggregation state and chemical composition of polysaccharides.…”
Section: Effect Of Biological Modifications On the Hypoglycemic And H...mentioning
confidence: 99%
“…Enzymes can alleviate hypoglycemia by binding the exposed hydroxyl groups to amino acid residues in digestive enzymes by breaking the glycosidic bonds of polysaccharides. This process inhibits the activity of α-glucosidase . Following complex enzymatic hydrolysis, the polysaccharide found in sweet potato stems and leaves markedly increased the inhibition rate of α-glucosidase and α-amylase, and this inhibition rate increased in a concentration-dependent manner as the polysaccharide concentration increased.…”
Section: Effect Of Structural Modifications On the Biological
Activit...mentioning
Polysaccharides
are an important class of biomolecules derived
from several sources. However, the inherent structure of polysaccharides
prevents them from exhibiting favorable physicochemical properties,
which restricts their development in agriculture, industry, food,
and biomedicine. This paper systematically summarizes the changes
in the primary and advanced structures of modified polysaccharides,
and focuses on the effects of various modification methods on the
hydrophobicity, rheological properties, emulsifying properties, antioxidant
activity, hypoglycemic, and hypolipidemic activities of polysaccharides.
Then there is a list the applications of modified polysaccharides
in treating heavy metal pollutants, purifying water resources, improving
beverage stability and bread quality, and precisely delivering the
drug. When summarized and reviewed, the information above can shed
further light on the relationship between polysaccharide structure
and function. Determining the structure–activity relationship
provides a scientific basis for the direction of molecular modifications
of polysaccharides.
“…Traditional degradation methods, such as chemical and physical degradation, suffer from various disadvantages such as byproduct formation, low target product yield, complex operations, and significant environmental pollution. 6 Recently, many functional oligosaccharides have been produced via enzymatic degradation methods, which offer advantages such as high yield, low environmental impact, mild reaction conditions, and minimal byproduct formation. 7 Baijiu, the national alcohol of China, is produced through a solid-state fermentation process that yields a brownish-yellow and viscous liquid called Huangshui (HS).…”
Section: Introductionmentioning
confidence: 99%
“…Currently, the industrial production of functional oligosaccharides mainly relies on monosaccharide synthesis and/or polysaccharide degradation methods. Traditional degradation methods, such as chemical and physical degradation, suffer from various disadvantages such as byproduct formation, low target product yield, complex operations, and significant environmental pollution . Recently, many functional oligosaccharides have been produced via enzymatic degradation methods, which offer advantages such as high yield, low environmental impact, mild reaction conditions, and minimal byproduct formation …”
Huangshui polysaccharide (HSP) has attracted more and more interest due to its potential health benefits. Despite being an excellent source for the preparation of oligosaccharides, there are currently no relevant research reports on HSP. In the present study, a novel oligosaccharide (HSO) with a molecular weight of 1791 Da and a degree of polymerization of 11 was prepared through enzymatic degradation of crude HSP (cHSP). Methylation and NMR analyses revealed that the main chain of HSO was (1 → 4)-α-D-glucose with two O-6-linked branched chains. Morphological observations indicated that HSO exhibited smooth surface with lamellar and filamentary structure, and the glycan size ranged from 0.03 to 0.20 μm. Notably, HSO significantly promoted the proliferation of Bif idobacterium, Bacteroides, and Phascolarctobacterium, thereby making positive alterations in intestinal microbiota composition. Moreover, HSO markedly increased the content of short-chain fatty acids during in vitro fermentation. Metabolomics analysis illustrated the important metabolic pathways primarily involving glucose metabolism, amino acid metabolism, and fatty acid metabolism.
The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022. As with previous review, this review also includes a few papers that describe methods appropriate to analysis by MALDI, such as sample preparation, even though the ionization method is not MALDI. The review follows the same format as previous reviews. It is divided into three sections: (1) general aspects such as theory of the MALDI process, matrices, derivatization, MALDI imaging, fragmentation, quantification and the use of computer software for structural identification. (2) Applications to various structural types such as oligo‐ and polysaccharides, glycoproteins, glycolipids, glycosides and biopharmaceuticals, and (3) other general areas such as medicine, industrial processes, natural products and glycan synthesis where MALDI is extensively used. Much of the material relating to applications is presented in tabular form. MALDI is still an ideal technique for carbohydrate analysis, particularly in its ability to produce single ions from each analyte and advancements in the technique and range of applications show little sign of diminishing.
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