Preparation, structural characterization, thermal properties and antifungal activity of alginate-CuO bionanocomposite

Safaei, Mohsen; Taran, Mojtaba; Imani, Mohammad Moslem

doi:10.1016/j.msec.2019.03.108

Cited by 55 publications

(17 citation statements)

References 49 publications

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“…The precise mechanism of action of the cobalt oxide nanoparticles, which kills the bacteria, is still unclear and no specific mechanism has been suggested in this regard. However, due to mechanisms of action of other nanoparticles, probably processes such as the induction of oxidative stress, the release of toxic metal ions and damage to the cell membrane and interfering its activities can generate the antimicrobial properties of cobalt oxide nanoparticles [25], [26].…”

Section: Discussionmentioning

confidence: 99%

Optimisation of Cobalt Oxide Nanoparticles Synthesis as Bactericidal Agents

Moradpoor

Safaei

Rezaei

et al. 2019

Open Access Maced J Med Sci

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AIM: With the increased bacterial resistance and the resulting problems in recent years, it seems necessary to find new biocompatible compounds to confront this problem. This research was conducted to optimise the synthesis of cobalt oxide nanoparticles with the highest antibacterial activity. METHODS: In the present study, 9 experiments were designed using the Taguchi method. The effect of three factors of cobalt nitrate, KOH and the stirring time in the synthesis of cobalt oxide nanoparticles with the highest antibacterial activity was investigated. The bactericidal effect of synthesised nanoparticles was evaluated using the colony-forming unit (CFU) and disk diffusion methods. The characteristics of nanoparticles were studied using the Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and the scanning electron microscopy (SEM). RESULTS: The results indicated that all three evaluated factors were effective on the antibacterial properties of the synthesised nanoparticles. The best antibacterial activity of cobalt oxide nanoparticles was observed in experiment 9 (cobalt nitrate 0.6 M, KOH 2M and stirring time 60 min). The study of nanoparticles synthesised by FTIR, XRD, and SEM confirmed the formation of cobalt oxide nanoparticles with size (24 nm) and a proper structure (spinel structure). CONCLUSION: Due to the optimal antibacterial properties of the synthesised cobalt oxide nanoparticles, they can be used in the fabrication of dental and medical equipment with antibacterial properties.

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Section: Discussionmentioning

confidence: 99%

Optimisation of Cobalt Oxide Nanoparticles Synthesis as Bactericidal Agents

Moradpoor

Safaei

Rezaei

et al. 2019

Open Access Maced J Med Sci

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“…Considering the antimicrobial properties of different types of nanoparticles, such as nanosilver, nano titanium and copper nanoparticles, one of their important applications is to control a variety of pathogens. Also, recent results have shown that gold nanoparticles and also magnetic nanomaterials due to their unique properties can be recruited in various areas of treatment and nanomedicine [21], [22], [23]. Researchers, through the exploitation of the outer surface of nanomaterials, have established nanoscale interactions between materials and biological systems to dramatically enhance their performance and create new structures [24].…”

Section: The Nanomaterials and Their Application In Medicinementioning

confidence: 99%

The Role of Nanomaterials in the Treatment of Diseases and Their Effects on the Immune System

Rezaei¹,

Safaei²,

Mozaffari³

et al. 2019

Open Access Maced J Med Sci

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Nanotechnology has been widely exploited in recent years in various applications. Different sectors of medicine and treatment have also focused on the use of nanoproducts. One of the areas of interest in the treatment measures is the interaction between nanomaterials and immune system components. Engineered nanomaterials can stimulate the inhibition or enhancement of immune responses and prevent the detection ability of the immune system. Changes in immune function, in addition to the benefits, may also lead to some damage. Therefore, adequate assessment of the novel nanomaterials seems to be necessary before practical use in treatment. However, there is little information on the toxicological and biological effects of nanomaterials, especially on the potential ways of contacting and handling nanomaterials in the body and the body response to these materials. Extensive variation and different properties of nanomaterials have made it much more difficult to access their toxicological effects to the present. The present study aims to raise knowledge about the potential benefits and risks of using the nanomaterials on the immune system to design and safely employ these compounds in therapeutic purposes.

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“…Gholizadeh et al [14] incorporated different contents of hydroxyapatite nanoparticles to alginate and obtained an improvement in physical and mechanical properties, as well as antimicrobial activity, compared to alginate [14]. The addition of CuO nanoparticles to alginate improved the thermal properties and also conferred antifungal activity, which is valuable in biomedical applications [15]. The incorporation of silicon dioxide to alginate further reduced the water vapor permeability and swelling degree and significantly increased the mechanical properties, important parameters for packaging industries [16].…”

Section: Introductionmentioning

confidence: 99%

Influence of Process Parameters in Graphene Oxide Obtention on the Properties of Mechanically Strong Alginate Nanocomposites

et al. 2020

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Sodium alginate, a biopolymer extracted from brown algae, has shown great potential for many applications, mainly due to its remarkable biocompatibility and biodegradability. To broaden its fields of applications and improve material characteristics, the use of nanoreinforcements to prepare nanocomposites with enhanced properties, such as carbonaceous structures which could improve thermal and mechanical behavior and confer new functionalities, is being studied. In this work, graphene oxide was obtained from graphite by using modified Hummers' method and exfoliation was assisted by sonication and centrifugation, and it was later used to prepare sodium alginate/graphene oxide nanocomposites. The effect that different variables, during preparation of graphene oxide, have on the final properties has been studied. Longer oxidation times showed higher degrees of oxidation and thus larger amount of oxygen-containing groups in the structure, whereas longer sonication times and higher centrifugation rates showed more exfoliated graphene sheets with lower sizes. The addition of graphene oxide to a biopolymeric matrix was also studied, considering the effect of processing and content of reinforcement on the material. Materials with reinforcement size-dependent properties were observed, showing nanocomposites with large flake sizes, better thermal stability, and more enhanced mechanical properties, reaching an improvement of 65.3% and 83.3% for tensile strength and Young's modulus, respectively, for a composite containing 8 wt % of graphene oxide.

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Preparation, structural characterization, thermal properties and antifungal activity of alginate-CuO bionanocomposite

Cited by 55 publications

References 49 publications

Optimisation of Cobalt Oxide Nanoparticles Synthesis as Bactericidal Agents

Optimisation of Cobalt Oxide Nanoparticles Synthesis as Bactericidal Agents

The Role of Nanomaterials in the Treatment of Diseases and Their Effects on the Immune System

Influence of Process Parameters in Graphene Oxide Obtention on the Properties of Mechanically Strong Alginate Nanocomposites

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