Preparation of α,α-difluoroalkanesulfonic acids

Copper(0)-mediated fluoroalkylation of iodobenzene with 2-bromo-1,1,2,2-tetrafluoroethyl compounds: Investigation on the influence of R substituent on the reactivity of RCF2Cu species

“…2-Bromo-1,1,2,2-tetrafluoroethyl compounds were prepared by using previously known methods (Scheme 3) [12][13][14]. Deoxyfluorination of 2-bromo-2,2-difluoroacetophenones with diethylaminosulfur trifluoride (DAST) readily gave (2-bromo-1,1,2,2-tetrafluoroethyl)arenes 8a [12] and 8b.…”

N-(2-bromotetrafluoroethyl) derivatives of five-membered nitrogen-containing heterocycles

“…Salts 8a-e with reactive sulfinic group can be used as a source for obtaining new sulfur-containing compounds because alkylation and oxydation reactions of polyfluoroalkanesulfinates were well studied [18,19].…”

New aryl-containing fluorinated sulfonic acids and their ammonium salts, useful as electrolytes for fuel cells or ionic liquids

“…So, we turned to the synthesis of the sulfonic acids corresponding to 2a and 2c which, in principle would be very strong and could be neutralized by a large variety of organic or inorganic bases. Only few references were found in the literature for the preparation of free aryl-containing perfluoroalkyl sulfonic acids by acidification of the corresponding sulfonate [16,17] (Fig. 1).…”

“…So, Prakash et al prepared 4a,b in a dynamic process, by elution of an acidic resin with an aqueous solution of the corresponding sulfonates. Consequently, they obtained the sulfonic acids as aqueous solutions, from which 4a,b could not be isolated by evaporation since they decomposed under heating [16]. On the other hand, as far as 5 is concerned, no experimental data are available.…”