Preparation of UV-filter encapsulated mesoporous silica with high sunscreen ability

Chen-Yang, Y. W.; Chen, Y.T.; Li, C.C.; Yu, Hao; Chuang, Yi-Chen; Su, Jiaxin; Lin, Yi‐Chun

doi:10.1016/j.matlet.2010.12.034

Cited by 38 publications

(11 citation statements)

References 13 publications

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“…It was found that encapsulation of octal methoxycinnamate in the MS matrix (MCX-MS) was ~65 wt. % of MCX-MS and increased its SPF value by 57% (137).…”

Section: Ms Have Been Extensively Utilised As Msn (107) Ms-microsphementioning

confidence: 95%

Porous Inorganic Drug Delivery Systems—a Review

et al. 2017

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Innovative methods and materials have been developed to overcome limitations associated with current drug delivery systems. Significant developments have led to the use of a variety of materials (as excipients) such as inorganic and metallic structures; marking a transition from conventional polymers. Inorganic materials, especially those possessing significant porosity, are emerging as good candidates for the delivery of a range of drugs (anti-biotics, anti-cancer and anti-inflammatories), providing several advantages in formulation and engineering (encapsulation of drug in amorphous form, controlled delivery and improved targeting). This review focuses on key selected developments in porous drug delivery systems. The review provides a short broad overview of porous polymeric materials for drug delivery before focusing on porous inorganic materials (e.g. Santa Barbara Amorphous (SBA) and Mobil Composition of Matter (MCM)) and their utilisation in drug dosage form development. Methods for their preparation and drug loading thereafter are detailed. Several examples of porous inorganic materials, drugs used and outcomes are discussed providing the reader with an understanding of advances in the field and realistic opportunities.

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“…It was found that encapsulation of octal methoxycinnamate in the MS matrix (MCX-MS) was ~65 wt. % of MCX-MS and increased its SPF value by 57% (137).…”

Section: Ms Have Been Extensively Utilised As Msn (107) Ms-microsphementioning

confidence: 95%

Porous Inorganic Drug Delivery Systems—a Review

et al. 2017

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“…Exploiting their high surface area, narrow poresize distribution and one-dimensional hexagonally ordered pore structure, these materials can represent suitable hosts for organic sunscreens [40]. In addition, the presence of freely accessible silanol groups inside the pores may be advantageous to further stabilize the embedded compounds [22].…”

Section: Inorganic Materialsmentioning

confidence: 99%

The real value of novel particulate carriers for sunscreen formulation

Blasi

Schoubben

Giovagnoli

et al. 2011

Expert Review of Dermatology

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Solar radiation is a consolidated environmental risk factor in the development of non-melanoma skin cancer and is responsible for sunburn and skin aging. By consequence, the use of sunscreen products is considered the best approach for skin protection. Today, sunscreen products are based on conventional formulations, such as creams, milks or gels, which do not protect chemical ultraviolet filters from photodegradation and allow their systemic absorption. In this article, innovative systems, namely clays, cyclodextrins, polymer and lipid microparticles, are discussed as potential sunscreen carriers to be embedded in the aforementioned formulations. Their capability to improve sunscreen performances, to reduce their potential toxicity issues and to overcome formulation problems are examined also

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“…In order to optimize the effectiveness of UV-filters several studies have combined the merits of the organic filters and inorganic filters to improve their UV-prevention abilities [7][8][9][10][11][12]. Similarly, our previous work have demonstrated the encapsulation of a liquid-type organic UVB-filter, Octylmethoxycinnamate (MCX), into the inorganic UV-filter mesoporous silica using in situ sol-gel process, and found about 57% enhancement on its in vitro sun protection factor (SPF) value [13]. To further include UVA filter ability, in yet another work we looked to a solidtype organic UVA-B filter, 2-hydroxy-4-methoxy-benzophenone (BP-3), which is widely used as cosmetic additive, pigment initiator, medicine, etc.…”

Section: Introductionmentioning

confidence: 99%

“…Specifically our study showed that not only the in vitro SPF but also the in vitro UV-A values of the MSBP-2-based sunscreen was increased by about 17% more than that of the free BP-3-based sunscreen. Although the adsorption method was a more economical method over encapsulation due to its simplicity which cuts down on cost and time; the improvement in SPF value was not as significant as what have been observed from the MS-encapsulated MCX UV-filter [13]. Therefore, in this work we set out to test the sunscreen ability of MS encapsulated BP-3 UV-filter (BESs) made through in situ so gel process.…”

Section: Introductionmentioning

confidence: 99%