Preparation of sock impregnated with microcapsules based on olive oil for the antibacterial and antifungal therapy of athlete's foot

Abstract

Athlete's foot is a cutaneous fungal infection caused by dermatophyte infection. It is characterised by itching, flaking, and fissuring of the skin. Fungal infection of the feet can cause white and soggy skin between the toes, dry and flaky soles, or reddening and blistering of the skin all over the foot. The sock is therefore an important area for development and relevant for overall improvements in comfort. clothing designated for athlete's foot in terms of antifungal sock are developed. A jersey garment is developed with cotton and elastane by circular knitting machine. The sock is improved by adding antifungal treatments. The improvement depends on the impregnation of ethylcellulose microcapsules with olive oil on the textile surface. Olive oil also has antibacterial and antifungal properties, making it very effective in treating infections and itching. The morphological characterization of the microcapsules was studied. Structural characterization, using Fourier Transform Infra-Red Spectroscopy, confirmed the encapsulation of the olive oil. Thermal characterization by Thermogravimetric Analysis and Differential Thermal Analysis showed the encapsulation of olive oil and the thermal stability with the charged microcapsules. The encapsulation efficiency is 64%. The release of olive oil from ethylcellulose microcapsules has been proven by studying the kinetic of diffusion through a pig skin. The liberation and the crossing of olive oil are studied through the pig skin. Then the pathological effect of microencapsulated socks is obtained together.

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“…This peak likely corresponds to specific chemical functionalities associated with the microcapsules. The peak at around 1737 cm −1 in the spectra of coco oil and ethylcellulose typically corresponds to C=O (carbonyl) stretching vibrations, which are common in ester or other carbonyl-containing groups [21,22]. This is a characteristic peak for many organic compounds, especially those that contain ester groups, as in ethylcellulose.…”

“…The interaction between the coco oil and the ethylcellulose may alter the electronic environment around the carbonyl groups, leading to a shift in the absorption frequency. It might indicate the formation of new chemical bonds or interactions, such as hydrogen bonding, due to the encapsulation process, that affect the carbonyl group's vibration frequency [20][21][22].…”