Preparation of silver nanoparticles using aqueous extracts of the red algae Laurencia aldingensis and Laurenciella sp. and their cytotoxic activities

Vieira, Adriana P.; Stein, Erika Mattos; Andreguetti, Daniel Xavier; Colepicolo, Pio; Ferreira, Ana Maria da Costa

doi:10.1007/s10811-015-0757-4

Cited by 28 publications

(10 citation statements)

References 55 publications

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“…Consequently, these cells require higher doses of cytotoxic agent in comparison to the non-resistant cells. 49 Therefore, these results show that the nanoparticles are equally toxic toward both the MDR (MES-SA/Dx5) and the non-resistant (MES-SA) cancer cell lines. This makes a-SeNPs a promising candidate to pharmaceutical agents to overcome resistance in cancer cells.…”

Section: Cytotoxicity Datamentioning

confidence: 75%

“Sweet Chemistry”: a Green Way for Obtaining Selenium Nanoparticles Active against Cancer Cells

Vieira¹,

Stein²,

Andreguetti³

et al. 2017

J. Braz. Chem. Soc.

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We present an environment friendly synthesis of selenium nanoparticles and the study of their cytotoxic activity against uterine sarcoma cancer and fibroblasts cells. Amorphous selenium (a-SeNPs) and trigonal selenium (t-SeNPs) were synthesized using D-fructose as the reducing agent and characterized by high-resolution transmission electron microscopy (HRTEM), energydispersive X-ray spectroscopy (EDX), powder X-ray diffraction analysis (XRD), inductively coupled plasma optical emission spectrometry (ICP OES), dynamic light scattering (DLS) to obtain zeta potential values and cyclic voltammetry (CV). Particularly, a-SeNPs presented high toxicity toward the resistant cancer cell line MES-SA/Dx5 and its parental MES-SA line. However, they are not toxic against P4 fibroblast cells in comparative studies. Keywords: selenium nanoparticles, D-fructose, cancer cells, green chemistry, cytotoxicity IntroductionSelenium is an essential element of significant importance not only for humans, but also for other forms of life. 1,2 Inorganic seleno-compounds have strong antioxidant activity, as well as some pro-oxidant effects and, additionally, have great importance in nutrition and medicine. 3,4 Epidemiological studies have already demonstrated the potential role of selenium in the prevention and treatment of cancer cells. [5][6][7] For example, selenium supplementation showed effective reduction in the incidence of cancer in the cervix, lung and liver. 8 However, the biological activity of elemental selenium stands opposite to the selenium salts, since selenite and selenate showed inadequate cytotoxicity to normal cells. [9][10][11] In this sense, nanoparticles of elemental selenium stand out as an alternative, due to its low toxicity and acceptable bioavailability. [12][13][14] Nanoparticles have become increasingly prominent in the medical field in the last few decades, giving rise to a new area, nanomedicine. This new area is focused on developing nanomaterials with potential use in therapy and diagnosis of diseases, [15][16][17] including selenium nanoparticles (SeNPs). 18Generally, the methods for obtaining SeNPs involve multiple steps, high temperatures and pressures; require expensive equipment and reagents, as well as being harmful to the environment. [19][20][21][22][23][24][25][26][27] In this sense, it is necessary to develop simple routes that focus on green chemistry and no harm to the environment. Research has demonstrated the use of microorganisms such as bacteria, to reduce selenite. This method is considered a clean synthesis, but the cost and time of preparation of microbiological cultures is a disadvantage. 28-30The use of plant extracts and biopolymers such as chitosan, konjac glucomannan, gum acacia, carboxymethyl cellulose, sodium alginate and glutathione, as reducing agents of selenite has also been an alternative, since they are highly biodegradable and non-toxic materials. However, in each of these works there are several processing steps "Sweet Chemistry": a Green Way for Obtaining Selenium Nanop...

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Section: Cytotoxicity Datamentioning

confidence: 75%

“Sweet Chemistry”: a Green Way for Obtaining Selenium Nanoparticles Active against Cancer Cells

Vieira¹,

Stein²,

Andreguetti³

et al. 2017

J. Braz. Chem. Soc.

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“…Among them sulfated polysaccharides of algal origins have been gaining attention as matrices for biomedical applications thanks to their ascertained bioactivity and chemical versatility. Recently polysaccharides-based extracts obtained from several seaweed species belonging to red, brown and green algae such as Ulva fasciata, Gracilaria birdiae, Turbinaria conoides, Chaetomorpha linum, Laurencia aldingensis, Sargassum siliquosum have been successfully used for the preparation of silver-based nanostructures (El-Rafie, El-Rafie, & Zahran, 2013; Kannan, Arumugam, Ramya, Manivannan, & Anantharaman, 2013;Rajeshkumar, Kannan, & Annadurai, 2013;Vasquez et al, 2016;Vieira, Stein, Andreguetti, Colepicolo, & Ferreira, 2016). Nevertheless, to the best of our knowledge ulvan, a sulfated polysaccharide extracted from green algae belonging to Ulva sp.…”

Section: Introductionmentioning

confidence: 99%

Ulvan as novel reducing and stabilizing agent from renewable algal biomass: Application to green synthesis of silver nanoparticles

Massironi

Morelli

Grassi

et al. 2019

Carbohydrate Polymers

109

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Silver nanoparticles (AgNPs) have been intensively investigated in virtue of their optical and antimicrobial properties, although their applications have been limited due to inherent toxicity and to the need of employing harsh chemical reagents for the synthesis. In this work, ulvan, a sulfated polysaccharide extracted from green algae belonging to Ulva armoricana sp., was for the first time investigated and identified as reducing and stabilizing agent for AgNPs synthesis by using milder conditions than those conventionally adopted by chemical methods. The synthesized AgNPs were thoroughly characterized to highlight the structure and the role exerted by ulvan in their synthesis and stabilization. The formation of AgNPs stabilized by a thick ulvan shell was assessed by UV-vis, XRD, TEM, DLS and zeta potential analyses. The developed Ulvan based AgNps showed an IC50 in the range of 10 μg/ml in Balb/3T3 mouse embryo fibroblasts and antimicrobial activity toward both Gram+and Gram − bacteria.

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“…Marine red algae produce high quantity of secondary metabolites [63], including sesquiterpenes, diterpenes, triterpenes and many other types that exert various biological activities such as antifungal, antibacterial, and anticancer activities [64].…”

Section: Rhodophytamentioning

confidence: 99%

An Overview to the Health Benefits of Seaweeds Consumption

2021

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Currently, seaweeds are gaining major attention due to the benefits they give to our health. Recent studies demonstrate the high nutritional value of seaweeds and the powerful properties that seaweeds’ bioactive compounds provide. Species of class Phaeophyceae, phylum Rhodophyta and Chlorophyta possess unique compounds with several properties that are potential allies of our health, which make them valuable compounds to be involved in biotechnological applications. In this review, the health benefits given by consumption of seaweeds as whole food or by assumption of bioactive compounds trough natural drugs are highlighted. The use of seaweeds in agriculture is also highlighted, as they assure soils and crops free from chemicals; thus, it is advantageous for our health. The addition of seaweed extracts in food, nutraceutical, pharmaceutical and industrial companies will enhance the production and consumption/usage of seaweed-based products. Therefore, there is the need to implement the research on seaweeds, with the aim to identify more bioactive compounds, which may assure benefits to human and animal health.

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Preparation of silver nanoparticles using aqueous extracts of the red algae Laurencia aldingensis and Laurenciella sp. and their cytotoxic activities

Cited by 28 publications

References 55 publications

“Sweet Chemistry”: a Green Way for Obtaining Selenium Nanoparticles Active against Cancer Cells

“Sweet Chemistry”: a Green Way for Obtaining Selenium Nanoparticles Active against Cancer Cells

Ulvan as novel reducing and stabilizing agent from renewable algal biomass: Application to green synthesis of silver nanoparticles

An Overview to the Health Benefits of Seaweeds Consumption

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