Preparation of regenerated silk fibroin/silk sericin fibers by coaxial electrospinning

Artificial Silk Materials with Enhanced Mechanical Properties and Controllable Structures

“…[13] Compared with the electrospun pure SF fibers, the coaxial SF/SS fibers had more stable structure with more β-sheet (and related intermediate) conformation and accordingly better thermostability and mechanical properties. Therefore, it is hypothesized that besides serving as an adhesive to bind two SF monofilaments together in cocoon, SS may also induce the conformational transition of SF to β-sheet structure.…”

Silk Protein Sericin: Promising Biopolymer for Biological and Biomedical Applications

“…Using coaxial electrospinning, regenerated fibroin and sericin aqueous solutions as the core and shell, respectively, with components and core-shell structure similar to the natural silkworm silk, have been investigated [42]. The availability of sericin nanofibers introduces a new set of possible uses for these small diameter fibers for cell proliferation purposes, nanocomposite reinforcing fibers for nanotechnology, wound dressing, scaffolds for tissue engineering and other biomedical applications.…”

Electrospun silk sericin nanofibers for biomedical applications

“…Recently, by mimicking the intrinsic characteristics of silkworm spinning, coaxial electrospinning was used with SF and SS aqueous solutions and shell spinning dopes in order to prepare SS/SF composites with binary components and core-shell structures (Hang et al ., 2012). It was found that the core dope (SF) fl ow rate and applied voltage had some effects on the morphology of the SS/SF composite fi ber.…”

“…The mechanical performance of the coaxial SF/SS and pure SF fi ber mats prepared by electrospinning is shown in Fig. 5.10 (Hang et al ., 2012). The average tensile strength and energy of coaxial SF/SS fi ber mats up to breaking point were increased by nearly 82% (to 1.93 MPa) and 93% (to 7.21 J/kg), respectively, compared to pure SF fi ber (Hang et al ., 2012).…”