Preparation of rare earth-doped nano-fluorescent materials in the second near-infrared region and their application in biological imaging

Zhu, Hetong; Ding, Xin; Wang, Chang; Cao, Mengyu; Yu, Bing; Cong, Hailin; Shen, Youqing

doi:10.1039/d3tb01987j

J. Mater. Chem. B

2024

DOI: 10.1039/d3tb01987j

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Preparation of rare earth-doped nano-fluorescent materials in the second near-infrared region and their application in biological imaging

Hetong Zhu,

Xin Ding,

Chang Wang

et al.

Abstract: The near-infrared (NIR) fluorescence imaging (FLI) has gained widespread interest in the biomedical field because of the advantages of highly sensitive and high penetration depth. In addition, near-infrared second (NIR-II)...

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NIR‐I Activated Orthogonal NIR‐IIb/c Emissions in a Lanthanide‐Doped Nanoparticle for Fluorescence Imaging and Information Encryption

Li,

Huang,

Zhu

et al. 2024

Advanced Science

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Applying the orthogonal principle for distinguishable second near‐infrared (NIR‐II) emissions has brought new dimensions for ratio fluorescence imaging (RFI) detection and information encryption, deepening the tissue detection depth and improving signal‐to‐noise ratio and information security. However, the orthogonal NIR‐II emissions underlying these advanced optical applications have been reported only in heterogeneous structures and mixtures, limiting their practicality and potential impact. Herein, NIR‐I‐activated orthogonal NIR‐IIb/c (1530/1825 nm) emissions nanoparticles (ONNPs) are developed by spatially separated doping of Tm3+ and Er3+ emitter upon switching 808 and 980 nm excitations. RFI techniques and orthogonal NIR‐II emission ONNPs are used to demonstrate vessel depth detection based on wavelength‐dependent optical attenuation properties in tissue. The superiority of the optical coding and encoding process in a 4 × 1 binary matrix is demonstrated for anticounterfeiting and decryption imaging of quick‐response (QR) code for information storage. The research progress of this NIR‐II orthogonal emissions probe will drive the development of biomedical sensing, imaging safety, and future biophotonics technologies.

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NIR‐I Activated Orthogonal NIR‐IIb/c Emissions in a Lanthanide‐Doped Nanoparticle for Fluorescence Imaging and Information Encryption

Li,

Huang,

Zhu

et al. 2024

Advanced Science

View full text Add to dashboard Cite

show abstract

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Preparation of rare earth-doped nano-fluorescent materials in the second near-infrared region and their application in biological imaging

Abstract: The near-infrared (NIR) fluorescence imaging (FLI) has gained widespread interest in the biomedical field because of the advantages of highly sensitive and high penetration depth. In addition, near-infrared second (NIR-II)...

Cited by 1 publication

References 209 publications

NIR‐I Activated Orthogonal NIR‐IIb/c Emissions in a Lanthanide‐Doped Nanoparticle for Fluorescence Imaging and Information Encryption

NIR‐I Activated Orthogonal NIR‐IIb/c Emissions in a Lanthanide‐Doped Nanoparticle for Fluorescence Imaging and Information Encryption

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