Preparation of Porphyrin-Based Unimolecular Micelles for Synergistic Photodynamic Therapy and Radiotherapy
Jiawei Song,
Shusu Ren,
Xiang Xu
et al.
Abstract:Polymeric carriers have been widely used in biomedical
fields because
of their strong structural tunability and biocompatibility, which
often proximately determine the in vivo behavior of the drug and are
crucial in practical application. In this work, porphyrin-based unimolecular
micelles with an average diameter less than 20 nm are developed by
light-mediated bromine–iodine transformation reversible-deactivation
radical polymerization (BIT-RDRP) for synergistic photodynamic therapy
(PDT) and radiotherapy (RT… Show more
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